Comparative genomics of closely related salmonellae

Robert A. Edwards, Gary J. Olsen, Stanley R. Maloy

Research output: Contribution to journalReview articlepeer-review

155 Citations (Scopus)


As the number of completed genome sequences increases, there is increasing emphasis on comparative genomic analysis of closely related organisms. Comparison of the similarities and differences between the five publicly available Salmonella genome sequences reveals extensive sequence conservation among the Salmonella serovars. However, horizontal gene transfer has provided each genome with between 10% and 12% of unique DNA. Genome comparisons of the closely related salmonellae emphasize the insights that can be gleaned from sequencing genomes of a single species.

Original languageEnglish
Pages (from-to)94-99
Number of pages6
JournalTrends in Microbiology
Issue number2
Publication statusPublished - 1 Feb 2002
Externally publishedYes


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