Comparing cartilage thickness and subchondral bone microarchitecture in varus- and valgus-aligned osteoarthritic tibiae with controls

Sophie Rapagna; Bryant Roberts; Lucien B Solomon; Karen J Reynolds; Dominic Thewlis; Egon Perilli

Comparing cartilage thickness and subchondral bone microarchitecture in varus- and valgus-aligned osteoarthritic tibiae with controls

Sophie Rapagna, Bryant Roberts, Lucien B Solomon, Karen J Reynolds, Dominic Thewlis, Egon Perilli

College of Science and Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

In knee osteoarthritis (OA), regional changes in proximal tibia subchondral trabecular bone (STB) microarchitecture and cartilage may reflect joint loading. However, reports on STB differences between OA and non-pathological joints are conflicting. Moreover, the effect of joint alignment on cartilage morphology (thickness) and underlying STB remains unexplored. This analysis in an ongoing study aims to quantify tibia cartilage and STB microarchitecture in end-stage knee OA patients with varus or valgus-aligned joints, comparing them to control (non-OA) knees.

Original language	English
Number of pages	1
Publication status	Published - 2018
Event	11th Australasian Biomechanics Conference (ABC11): Pre-conference workshop: Mechanical factors in Osteoarthritis - Auckland, New Zealand Duration: 3 Dec 2018 → 5 Dec 2018 https://www.anzsb.asn.au/abc

Conference

Conference	11th Australasian Biomechanics Conference (ABC11)
Abbreviated title	ABC11
Country/Territory	New Zealand
City	Auckland
Period	3/12/18 → 5/12/18
Other	A focus of having this year's ABC meeting in New Zealand is to strengthen the bond between Australian and New Zealand biomechanists by highlighting the breadth and quality of biomechanics research currently being undertaken in research institutes across New Zealand.
Internet address	https://www.anzsb.asn.au/abc

Keywords

cartilage
knee
alignment

Cite this

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title = "Comparing cartilage thickness and subchondral bone microarchitecture in varus- and valgus-aligned osteoarthritic tibiae with controls",

abstract = "In knee osteoarthritis (OA), regional changes in proximal tibia subchondral trabecular bone (STB) microarchitecture and cartilage may reflect joint loading. However, reports on STB differences between OA and non-pathological joints are conflicting. Moreover, the effect of joint alignment on cartilage morphology (thickness) and underlying STB remains unexplored. This analysis in an ongoing study aims to quantify tibia cartilage and STB microarchitecture in end-stage knee OA patients with varus or valgus-aligned joints, comparing them to control (non-OA) knees.",

keywords = "cartilage, knee, alignment",

author = "Sophie Rapagna and Bryant Roberts and Solomon, {Lucien B} and Reynolds, {Karen J} and Dominic Thewlis and Egon Perilli",

year = "2018",

language = "English",

note = "11th Australasian Biomechanics Conference (ABC11) : Pre-conference workshop: Mechanical factors in Osteoarthritis, ABC11 ; Conference date: 03-12-2018 Through 05-12-2018",

url = "https://www.anzsb.asn.au/abc",

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TY - CONF

T1 - Comparing cartilage thickness and subchondral bone microarchitecture in varus- and valgus-aligned osteoarthritic tibiae with controls

AU - Rapagna, Sophie

AU - Roberts, Bryant

AU - Solomon, Lucien B

AU - Reynolds, Karen J

AU - Thewlis, Dominic

AU - Perilli, Egon

PY - 2018

Y1 - 2018

N2 - In knee osteoarthritis (OA), regional changes in proximal tibia subchondral trabecular bone (STB) microarchitecture and cartilage may reflect joint loading. However, reports on STB differences between OA and non-pathological joints are conflicting. Moreover, the effect of joint alignment on cartilage morphology (thickness) and underlying STB remains unexplored. This analysis in an ongoing study aims to quantify tibia cartilage and STB microarchitecture in end-stage knee OA patients with varus or valgus-aligned joints, comparing them to control (non-OA) knees.

AB - In knee osteoarthritis (OA), regional changes in proximal tibia subchondral trabecular bone (STB) microarchitecture and cartilage may reflect joint loading. However, reports on STB differences between OA and non-pathological joints are conflicting. Moreover, the effect of joint alignment on cartilage morphology (thickness) and underlying STB remains unexplored. This analysis in an ongoing study aims to quantify tibia cartilage and STB microarchitecture in end-stage knee OA patients with varus or valgus-aligned joints, comparing them to control (non-OA) knees.

KW - cartilage

KW - knee

KW - alignment

UR - http://abc11.nz/wp-content/uploads/2018/12/ABC11-Programme-Update-03.12.2018.pdf

M3 - Paper

T2 - 11th Australasian Biomechanics Conference (ABC11)

Y2 - 3 December 2018 through 5 December 2018

ER -

Comparing cartilage thickness and subchondral bone microarchitecture in varus- and valgus-aligned osteoarthritic tibiae with controls

Abstract

Conference

Keywords

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