Constitutively active Rheb mutants [T23M] and [E40K] drive increased production and secretion of recombinant protein in Chinese hamster ovary cells

Medicine & Life Sciences

• Biological Products 9%
• Biotechnology 11%
• Cell Count 7%
• Cricetulus 61%
• Cultured Cells 8%
• Endoplasmic Reticulum 9%
• Growth 4%
• Guanosine Triphosphate 10%
• Health Care Sector 11%
• Immunoglobulins 8%
• Industry 8%
• Luciferases 27%
• Mechanistic Target of Rapamycin Complex 1 12%
• Monoclonal Antibodies 7%
• Monomeric GTP-Binding Proteins 11%
• Ovary 50%
• Protein Kinases 8%
• Proteins 21%
• Recombinant Proteins 57%
• Ribosomes 10%
• Serum 4%
• Therapeutics 1%

Engineering & Materials Science

• Biotechnology 10%
• Cells 56%
• Industry 3%
• Proteins 52%
• Recombinant proteins 100%

Chemical Compounds

• Amount 4%
• Anabolic 16%
• Biotechnology 12%
• Drug 6%
• Industry 8%
• Mammalian Cell 12%
• Protein 23%
• Protein Synthesis 24%