@article{c44f756e55c6444586c4bff37eef97bf,
title = "Continuation of therapeutic dose heparin for critically ill patients with COVID-19",
abstract = "Randomized trials demonstrated improved clinical outcomes when therapeutic-dose heparin is administered to non-critically ill patients hospitalized for coronavirus disease 2019 (COVID-19) and this is now recommended in practice guidelines. In contrast, clinical trials showed that therapeutic-dose heparin is not beneficial, and potentially harmful, when initiated in critically ill patients. Therefore, it is uncertain whether therapeutic-dose heparin should continue or be dose reduced when a patient transitions from non-critically ill to critically ill...",
keywords = "COVID-19, Heparin, Drug therapy, Patient outcomes",
author = "Bradbury, {Charlotte A.} and Lawler, {Patrick R.} and McVerry, {Bryan J.} and Ryan Zarychanski and {on behalf of the REMAP-C. A. P. Investigators} and Farah Al-Beidh and Angus, {Derek C.} and Arabi, {Yaseen M.} and Diptesh Aryal and Djillali Annane and Abi Beane and Berry, {Lindsay R.} and Scott Berry and Zahra Bhimani and Shailesh Bihari and Bonten, {Marc J.M.} and Brunkhorst, {Frank M.} and Meredith Buxton and Adrian Buzgau and Marc Carrier and Cheng, {Allen C.} and Matthew Cove and Derde, {Lennie P.G.} and Detry, {Michelle A.} and Estcourt, {Lise J.} and Fergusson, {Dean A.} and Mark Fitzgerald and Fowler, {Robert A.} and Girard, {Timothy D.} and Goligher, {Ewan C.} and Herman Goossens and Gordon, {Anthony C.} and Cameron Green and Rashan Haniffa and Higgins, {Alisa M.} and Thomas Hills and Huang, {David T.} and Horvat, {Christopher M.} and Hunt, {Beverley J.} and Nao Ichihara and Devachandran Jayakumar and Anand Kumar and Laffan, {Michael A.} and Francois Lamontagne and Leavis, {Helen L.} and Lewis, {Roger J.} and Linstrum, {Kelsey M.} and Edward Litton and Elizabeth Lorenzi and Lother, {Sylvain A.} and Marshall, {John C.} and McArthur, {Colin J.} and McAuley, {Daniel F.} and Anna McGlothlin and McGuinness, {Shay P.} and Saskia Middeldorp and Srinivas Murthy and Zoe McQuilten and Mouncey, {Paul R.} and Neal, {Matthew D.} and Nichol, {Alistair D.} and Parke, {Rachael L.} and Parker, {Jane C.} and Asad Patanwala and Luis Reyes and Rowan, {Kathryn M.} and Hiroki Saito and Santos, {Marlene S.} and Saunders, {Christina T.} and Schutgens, {Roger E.G.} and Ary Serpa-Neto and Seymour, {Christopher W.} and Manu Shankar-Hari and Vanessa Singh and Stanworth, {Simon J.} and Timo Tolppa and Turgeon, {Alexis F.} and Turner, {Anne M.} and {van Bentum-Puijk}, Wilma and {van de Veerdonk}, {Frank L.} and Webb, {Steve A.}",
year = "2023",
month = jul,
doi = "10.1007/s00134-023-07095-8",
language = "English",
volume = "49",
pages = "873--875",
journal = "Intensive Care Medicine",
issn = "0342-4642",
publisher = "Springer Verlag",
number = "7",
}