Contributions of ON and OFF pathways to emmetropization and form deprivation myopia in mice

Machelle T. Pardue, Ranjay Chakraborty, Hanna Park, Curran Sidhu, P. Michael Iuvone

Research output: Contribution to conferenceAbstract

Abstract

The exact visual signals that modulate visually-driven eye growth are not known. ON and OFF pathways are essential for processing information about contrast sensitivity and illumination. In addition, ON pathway stimulation increases retinal dopamine levels, a key modulator of myopic eye growth. To determine the role of ON and OFF
retinal pathways in emmetropization and form-deprivation myopia, we examined mouse models with defects in these pathways.
Original languageEnglish
Pages6-6
Number of pages1
DOIs
Publication statusPublished - Sep 2015
Externally publishedYes
Event15th International Myopia Conference - Wenzhou, China
Duration: 23 Sep 201527 Sep 2015

Conference

Conference15th International Myopia Conference
CountryChina
CityWenzhou
Period23/09/1527/09/15

Bibliographical note

© The Author(s). 2016 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Keywords

  • form deprivation myopia
  • mice
  • refractive development

Fingerprint Dive into the research topics of 'Contributions of ON and OFF pathways to emmetropization and form deprivation myopia in mice'. Together they form a unique fingerprint.

  • Cite this

    Pardue, M. T., Chakraborty, R., Park, H., Sidhu, C., & Iuvone, P. M. (2015). Contributions of ON and OFF pathways to emmetropization and form deprivation myopia in mice. 6-6. Abstract from 15th International Myopia Conference, Wenzhou, China. https://doi.org/10.1186/s40662-016-0057-3