Controversies in liver transplantation:: Acute alcoholic hepatitis and colorectal cancer liver metastases

Josipa Petric; Savio Barreto

Controversies in liver transplantation: Acute alcoholic hepatitis and colorectal cancer liver metastases

College of Medicine and Public Health

Research output: Contribution to journal › Review article › peer-review

Abstract

Liver transplantation (LT) is a life-saving operation but, with a limited donor pool, especially in Australia and New Zealand, patient selection for the waitlist remains crucial. The indication for LT should be assessed independent of the aetiology. Whilst there have been challenges in justifying LT for patients with acute alcoholic hepatitis (AH) and unresectable colorectal cancer liver metastases (CRLM) owing to previous reports of poor survival rates, the evidence landscape is changing. The aim of this manuscript is to review these specific, and evolving, indications for LT, namely AH and CRLM.

Original language	English
Pages (from-to)	6-11
Number of pages	6
Journal	Transplant Journal of Australasia
Volume	31
Issue number	1
Publication status	Published - Apr 2022

Keywords

Outcomes
Morbidity
Mortality
Stomach
Pancreas
Colon

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

https://search.informit.org/doi/10.3316/informit.410553221139497Licence: In Copyright

Cite this

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title = "Controversies in liver transplantation:: Acute alcoholic hepatitis and colorectal cancer liver metastases",

abstract = "Liver transplantation (LT) is a life-saving operation but, with a limited donor pool, especially in Australia and New Zealand, patient selection for the waitlist remains crucial. The indication for LT should be assessed independent of the aetiology. Whilst there have been challenges in justifying LT for patients with acute alcoholic hepatitis (AH) and unresectable colorectal cancer liver metastases (CRLM) owing to previous reports of poor survival rates, the evidence landscape is changing. The aim of this manuscript is to review these specific, and evolving, indications for LT, namely AH and CRLM.",

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author = "Josipa Petric and Savio Barreto",

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journal = "Transplant Journal of Australasia",

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T1 - Controversies in liver transplantation:

T2 - Acute alcoholic hepatitis and colorectal cancer liver metastases

AU - Petric, Josipa

AU - Barreto, Savio

PY - 2022/4

Y1 - 2022/4

N2 - Liver transplantation (LT) is a life-saving operation but, with a limited donor pool, especially in Australia and New Zealand, patient selection for the waitlist remains crucial. The indication for LT should be assessed independent of the aetiology. Whilst there have been challenges in justifying LT for patients with acute alcoholic hepatitis (AH) and unresectable colorectal cancer liver metastases (CRLM) owing to previous reports of poor survival rates, the evidence landscape is changing. The aim of this manuscript is to review these specific, and evolving, indications for LT, namely AH and CRLM.

AB - Liver transplantation (LT) is a life-saving operation but, with a limited donor pool, especially in Australia and New Zealand, patient selection for the waitlist remains crucial. The indication for LT should be assessed independent of the aetiology. Whilst there have been challenges in justifying LT for patients with acute alcoholic hepatitis (AH) and unresectable colorectal cancer liver metastases (CRLM) owing to previous reports of poor survival rates, the evidence landscape is changing. The aim of this manuscript is to review these specific, and evolving, indications for LT, namely AH and CRLM.

KW - Outcomes

KW - Morbidity

KW - Mortality

KW - Stomach

KW - Pancreas

KW - Colon

M3 - Review article

SN - 1323-5109

VL - 31

SP - 6

EP - 11

JO - Transplant Journal of Australasia

JF - Transplant Journal of Australasia

IS - 1