Convolutional neural networks for brain tumour segmentation

Abhishta Bhandari, Jarrad Koppen, Marc Agzarian

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

The introduction of quantitative image analysis has given rise to fields such as radiomics which have been used to predict clinical sequelae. One growing area of interest for analysis is brain tumours, in particular glioblastoma multiforme (GBM). Tumour segmentation is an important step in the pipeline in the analysis of this pathology. Manual segmentation is often inconsistent as it varies between observers. Automated segmentation has been proposed to combat this issue. Methodologies such as convolutional neural networks (CNNs) which are machine learning pipelines modelled on the biological process of neurons (called nodes) and synapses (connections) have been of interest in the literature. We investigate the role of CNNs to segment brain tumours by firstly taking an educational look at CNNs and perform a literature search to determine an example pipeline for segmentation. We then investigate the future use of CNNs by exploring a novel field—radiomics. This examines quantitative features of brain tumours such as shape, texture, and signal intensity to predict clinical outcomes such as survival and response to therapy.

Original languageEnglish
Article number77
Number of pages9
JournalInsights into Imaging
Volume11
DOIs
Publication statusPublished - 8 Jun 2020

Bibliographical note

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Keywords

  • Artificial intelligence
  • Convolutional neural network
  • Glioblastoma
  • Segmentation

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