Correlation of the severity of diabetic retinopathy and the heart muscle perfusion in patients with type 2 diabetes

Wieslaw Tryniszewski, Jaroslaw Kusmierczyk, Zbigniew Maziarz, Roman Gos, Dimitri Mikhailidis, Maciej Banach, Jacek Rysz, Konrad Pesudovs

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    8 Citations (Scopus)

    Abstract

    Objective: The objective was to investigate whether microvascular disturbances in patients with type 2 diabetes (DM) as defined by retinal examination predict the existence of macrovascular disturbances found on radioisotopic perfusion examinations of the heart muscle. Materials and methods: A total of 100 patients with type 2 DM and an additional cardiovascular risk factor were enrolled in the study. All patients underwent comprehensive ophthalmologic examination, including fundus color photography and fluorescein angiography, and were divided into three groups: group 1 (NoDR): met the inclusion criteria but had no diabetic retinopathy; group 2 (NPDR): had signs of nonproliferative diabetic retinopathy; group 3 (PDR): had signs of preproliferative or proliferative diabetic retinopathy. After collecting general medical history and clinical data, patients underwent heart muscle perfusion studies. All patients followed a 48-h protocol heart muscle perfusion examination in the rest state as well as after the standardized exercise test. Single photon emission computed tomography examination was performed. Results: In the PDR group, the impairment of the heart muscle perfusion at stress and rest was more frequent than in the NPDR and NoDR groups. Analysis of the heart muscle perfusion results for the three groups showed a significant relationship with the severity of microvascular complications observed in eye fundus examinations. Conclusions: Comprehensive ophthalmologic assessment of the progression of diabetic retinopathy in patients with type 2 DM may be an indicator of heart muscle perfusion disturbance.

    Original languageEnglish
    Pages (from-to)253-257
    Number of pages5
    JournalJournal of Diabetes and Its Complications
    Volume25
    Issue number4
    DOIs
    Publication statusPublished - Jul 2011

    Keywords

    • Diabetes
    • Diabetic retinopathy
    • Heart muscle
    • Risk factor

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  • Cite this

    Tryniszewski, W., Kusmierczyk, J., Maziarz, Z., Gos, R., Mikhailidis, D., Banach, M., Rysz, J., & Pesudovs, K. (2011). Correlation of the severity of diabetic retinopathy and the heart muscle perfusion in patients with type 2 diabetes. Journal of Diabetes and Its Complications, 25(4), 253-257. https://doi.org/10.1016/j.jdiacomp.2011.02.003