The crystal structure of the title compound, namely hydroxyimino(N, N’-dimethyl)malonamide (MeNHCOC(=NOH)CONHMe), has been determined by single-crystal X-ray diffraction with diffractometer data at 295 K. The structure was solved by direct methods and refined by least squares to a residual of 0.055 for 1477 observed reflections. Crystal data: monoclinic, P21/n, a 15.508(3), b 10.544(2), c 9.377(1) Å, β 103.15(2)°, Z 8. The two crystallographically independent molecules exhibit little conjugation throughout the C-C-C skeleton (<C-C> 1.50 Å), the molecule being non-planar. <C=O> is 1.234, <N-CH3> 1.443, <OC-N> 1.323, <C-NO> 1.278 and (N-O) 1.375 Å. The geometry is compared with those observed for several related derivatives.