TY - JOUR
T1 - CSF Brain-Reactive Autoantibodies are Elevated in Patients with Viral Encephalitis
AU - Yu, Zhong Yuan
AU - Wang, Jian Hong
AU - Li, Wei Wei
AU - Wang, Ye Ran
AU - Mañucat-Tan, Noralyn B.
AU - Wang, Jun
AU - Wang, Ju
AU - Cui, Gao Yu
AU - Pan, Jie Xiang
AU - Zhang, Shui Xian
AU - Liu, Zu Juan
AU - Tan, Liang
AU - Liu, Yu Hui
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Brain-reactive autoantibodies are thought to play an important role in mediating disorders of the central nervous system (CNS). These antibodies direct the processes underlying several diseases, such as multiple sclerosis (MS), neuromyelitis optica (NMO), and neuropsychiatric systemic lupus erythematosus [1,2,3]. In infectious diseases of the CNS, the pathogen itself is regarded to play a major role in the pathogenesis [4]. In recent years, post-viral autoimmune reactions have been identified to be critical factors that influence the pathogenesis [5, 6]. The best understood example is anti-NMDAR (N-methyl-d-aspartate receptor) encephalitis [7], which is commonly caused by viral infections, especially by herpes simplex virus (HSV) infection.
AB - Brain-reactive autoantibodies are thought to play an important role in mediating disorders of the central nervous system (CNS). These antibodies direct the processes underlying several diseases, such as multiple sclerosis (MS), neuromyelitis optica (NMO), and neuropsychiatric systemic lupus erythematosus [1,2,3]. In infectious diseases of the CNS, the pathogen itself is regarded to play a major role in the pathogenesis [4]. In recent years, post-viral autoimmune reactions have been identified to be critical factors that influence the pathogenesis [5, 6]. The best understood example is anti-NMDAR (N-methyl-d-aspartate receptor) encephalitis [7], which is commonly caused by viral infections, especially by herpes simplex virus (HSV) infection.
KW - brain-reactive autoantibodies
KW - Autoantibodies
KW - viral encephalitis
KW - Central Nervous System
UR - http://www.scopus.com/inward/record.url?scp=85084206148&partnerID=8YFLogxK
U2 - 10.1007/s12264-020-00503-9
DO - 10.1007/s12264-020-00503-9
M3 - Letter
C2 - 32350799
AN - SCOPUS:85084206148
VL - 36
SP - 942
EP - 946
JO - Neuroscience Bulletin
JF - Neuroscience Bulletin
SN - 1673-7067
IS - 8
ER -