Current Australian practice in the prevention and management of corneal allograft rejection

Nigel H. Barker, Timothy R.M. Henderson, Carolyn A. Ross, Douglas J. Coster, Keryn A. Williams

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    Purpose: To determine current practice in the prevention and management of corneal allograft rejection in Australia. Methods: A questionnaire was circulated to attendees at the 1998 Eye Bank Meeting in Adelaide. Twenty-four responses were received and analysed. Results: All respondents used topical corticosteroids for routine prophylaxis and to treat established rejection episodes. Prednisolone acetate was the most frequently prescribed topical corticosteroid. Systemic non-steroidal immunosuppression was prescribed almost exclusively for high-risk grafts. Seventy-five per cent of surgeons used systemic antiviral agents for the treatment of graft rejection in patients with Herpes simplex keratitis. Conclusion: There was a wide variation amongst surgeons in the choice of therapy for routine prophylactic immuno-suppression as well as for the treatment of established corneal allograft rejection.

    Original languageEnglish
    Pages (from-to)357-360
    Number of pages4
    JournalClinical and Experimental Ophthalmology
    Volume28
    Issue number5
    DOIs
    Publication statusPublished - Oct 2000

    Keywords

    • Antiviral agents
    • Corneal graft rejection
    • Corticosteroids
    • Immunosuppression
    • Penetrating keratoplasty

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