Current controversies in chronic obstructive pulmonary disease: A report from the global initiative for chronic obstructive lung disease scientific committee

Gerard J. Criner, Fernando J. Martinez, Shawn Aaron, Alvar Agustí, Antonio Anzueto, Mona Bafadhel, Peter J. Barnes, Jean Bourbeau, Rongchang Chen, Jeffrey Ewig, Leonardo M. Fabbri, Peter Frith, David M.G. Halpin, Mei Lan Han, Maria Montes de Oca, Masaharu Nishimura, Denis O’Donnell, Alberto Papi, Ian Pavord, Nicolas RocheRoberto Rodriguez-Roisin, Sundeep Salvi, Dave Singh, Don D. Sin, Robert Stockley, M. Victorina López Varela, Jørgen Vestbo, Claus F. Vogelmeier, George Washko, Jadwiga A. Wedzicha, Bartolome R. Celli

    Research output: Contribution to journalReview article

    5 Citations (Scopus)

    Abstract

    Chronic obstructive pulmonary disease (COPD) is a preventable and treatable leading cause of worldwide morbidity and mortality that markedly increases healthcare costs. Smoking cessation, vaccinations, supplemental oxygen for hypoxemic patients, and lung volume reduction surgery in selected patients all improve survival; smoking cessation also attenuates disease progression. Several inhaled, oral, and systemically administered drugs improve lung function, decrease the frequency and severity of COPD exacerbations, and improve patients’ quality of life. Pulmonary rehabilitation, noninvasive ventilation, and lung volume reduction also improve outcomes in selected patients. Despite these efforts, COPD continues to claim many lives and disable many more. COPD is a complex process with protean pulmonary and nonpulmonary manifestations punctuated by episodic escalations of respiratory symptoms in a predominately older patient population with multiple comorbid conditions.
    Original languageEnglish
    Pages (from-to)29-39
    Number of pages11
    JournalAnnals of the American Thoracic Society
    Volume16
    Issue number1
    DOIs
    Publication statusPublished - Jan 2019

    Keywords

    • COPD
    • smoking
    • vaccination

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  • Cite this

    Criner, G. J., Martinez, F. J., Aaron, S., Agustí, A., Anzueto, A., Bafadhel, M., Barnes, P. J., Bourbeau, J., Chen, R., Ewig, J., Fabbri, L. M., Frith, P., Halpin, D. M. G., Han, M. L., Montes de Oca, M., Nishimura, M., O’Donnell, D., Papi, A., Pavord, I., ... Celli, B. R. (2019). Current controversies in chronic obstructive pulmonary disease: A report from the global initiative for chronic obstructive lung disease scientific committee. Annals of the American Thoracic Society, 16(1), 29-39. https://doi.org/10.1513/AnnalsATS.201808-557PS