TY - JOUR
T1 - Current controversies in chronic obstructive pulmonary disease
T2 - A report from the global initiative for chronic obstructive lung disease scientific committee
AU - Criner, Gerard J.
AU - Martinez, Fernando J.
AU - Aaron, Shawn
AU - Agustí, Alvar
AU - Anzueto, Antonio
AU - Bafadhel, Mona
AU - Barnes, Peter J.
AU - Bourbeau, Jean
AU - Chen, Rongchang
AU - Ewig, Jeffrey
AU - Fabbri, Leonardo M.
AU - Frith, Peter
AU - Halpin, David M.G.
AU - Han, Mei Lan
AU - Montes de Oca, Maria
AU - Nishimura, Masaharu
AU - O’Donnell, Denis
AU - Papi, Alberto
AU - Pavord, Ian
AU - Roche, Nicolas
AU - Rodriguez-Roisin, Roberto
AU - Salvi, Sundeep
AU - Singh, Dave
AU - Sin, Don D.
AU - Stockley, Robert
AU - López Varela, M. Victorina
AU - Vestbo, Jørgen
AU - Vogelmeier, Claus F.
AU - Washko, George
AU - Wedzicha, Jadwiga A.
AU - Celli, Bartolome R.
PY - 2019/1
Y1 - 2019/1
N2 - Chronic obstructive pulmonary disease (COPD) is a preventable and treatable leading cause of worldwide morbidity and mortality that markedly increases healthcare costs. Smoking cessation, vaccinations, supplemental oxygen for hypoxemic patients, and lung volume reduction surgery in selected patients all improve survival; smoking cessation also attenuates disease progression. Several inhaled, oral, and systemically administered drugs improve lung function, decrease the frequency and severity of COPD exacerbations, and improve patients’ quality of life. Pulmonary rehabilitation, noninvasive ventilation, and lung volume reduction also improve outcomes in selected patients. Despite these efforts, COPD continues to claim many lives and disable many more. COPD is a complex process with protean pulmonary and nonpulmonary manifestations punctuated by episodic escalations of respiratory symptoms in a predominately older patient population with multiple comorbid conditions.
AB - Chronic obstructive pulmonary disease (COPD) is a preventable and treatable leading cause of worldwide morbidity and mortality that markedly increases healthcare costs. Smoking cessation, vaccinations, supplemental oxygen for hypoxemic patients, and lung volume reduction surgery in selected patients all improve survival; smoking cessation also attenuates disease progression. Several inhaled, oral, and systemically administered drugs improve lung function, decrease the frequency and severity of COPD exacerbations, and improve patients’ quality of life. Pulmonary rehabilitation, noninvasive ventilation, and lung volume reduction also improve outcomes in selected patients. Despite these efforts, COPD continues to claim many lives and disable many more. COPD is a complex process with protean pulmonary and nonpulmonary manifestations punctuated by episodic escalations of respiratory symptoms in a predominately older patient population with multiple comorbid conditions.
KW - COPD
KW - smoking
KW - vaccination
UR - http://www.scopus.com/inward/record.url?scp=85059235125&partnerID=8YFLogxK
U2 - 10.1513/AnnalsATS.201808-557PS
DO - 10.1513/AnnalsATS.201808-557PS
M3 - Review article
C2 - 30427736
AN - SCOPUS:85059235125
SN - 2325-6621
VL - 16
SP - 29
EP - 39
JO - Annals of the American Thoracic Society
JF - Annals of the American Thoracic Society
IS - 1
ER -
