Degradation of forensic DNA profiles

Jo-Anne Bright, Duncan Taylor, James Curran, John Buckleton

    Research output: Contribution to journalArticlepeer-review

    33 Citations (Scopus)

    Abstract

    Selected profiles typed at the Promega PowerPlex 21 (PP21) loci were examined to determine if a linear or exponential model best described the relationship between peak height and molecular weight. There were fewer large departures from observed and expected peak heights using the exponential model. The larger differences that were observed were exclusively at the high molecular weight loci. We conclude that the data supports the use of an exponential curve to model peak heights versus molecular weight in PP21 profiles. We believe this observation will improve our ability to model expected peak heights for use in DNA interpretation software.

    Original languageEnglish
    Pages (from-to)445-449
    Number of pages5
    JournalAustralian Journal of Forensic Sciences
    Volume45
    Issue number4
    DOIs
    Publication statusPublished - 2013

    Keywords

    • degradation
    • forensic DNA
    • PowerPlex 21

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