Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus

Ke Li, Qiao-Lian Li, Nai-Yun Ji, Bo Liu, Wei Zhang, Xupeng Cao

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    One new nucleoside derivative, named 3-acetyl-5-methyl-2′- deoxyuridine (1), along with two known compounds 3,5-dimethyl-2′- deoxyuridine (2) and 3-methyl-2′-deoxyuridine (3), were isolated from the cultures of Streptomyces microflavus. This strain was an associated actinomycete isolated from the marine sponge Hymeniacidon perlevis collected from the coast of Dalian (China). Their structures were elucidated by detailed NMR and MS spectroscopic analysis as well as comparison with literature data.

    Original languageEnglish
    Pages (from-to)690-695
    Number of pages6
    JournalMarine Drugs
    Issue number5
    Publication statusPublished - May 2011


    • Actinomycete
    • Deoxyuridine
    • Hymeniacidon perlevis
    • Streptomyces microflavus

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