Depletion of B Lymphocytes in Chronic Hypoplastic Marrow Failure (Aplastic Anaemia)

Alec Morley, Kerry Holmes, Ian Forbes

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Summary: The numbers of B and T lymphocytes were measured in nine patients with chronic hypoplastic marrow failure and significant depletion of B but not of T lymphocytes was found. The lesion in the disease therefore appears to affect lymphopoiesis in addition to myelopoiesis. Study of surface immunoglobulin markers in three patients provided no evidence of clonal nature of the lymphocytes in the disease.

Original languageEnglish
Pages (from-to)538-541
Number of pages4
JournalAustralian and New Zealand Journal of Medicine
Issue number6
Publication statusPublished - Dec 1974
Externally publishedYes


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