Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria

Marie Claire Seeley; Tilenka R. Thynne; Wilton J. Braund; Daniel L. Worthley; Celine Gallagher; Prashanthan Sanders; Dennis H. Lau

doi:10.1016/j.amjmed.2021.03.028

Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria

Marie Claire Seeley, Tilenka R. Thynne, Wilton J. Braund, Daniel L. Worthley, Celine Gallagher, Prashanthan Sanders, Dennis H. Lau

College of Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

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Abstract

To the Editor:
Hypovolemia is a well-recognized phenotype in patients with postural tachycardia syndrome. Previous work has identified paradoxical low renin-aldosterone levels and red blood cell deficit as indicators of a potential renal cause for postural tachycardia syndrome. Here we present the first published report of postural tachycardia syndrome exacerbation due to partial central diabetes insipidus (pCDI)-related polyuria and hypovolemia, and successful treatment following chronic desmopressin (DDAVP) therapy.

Original language	English
Pages (from-to)	e486-e487
Number of pages	2
Journal	American Journal of Medicine
Volume	134
Issue number	9
Early online date	16 Apr 2021
DOIs	https://doi.org/10.1016/j.amjmed.2021.03.028
Publication status	Published - Sept 2021

Keywords

postural tachycardia syndrome
case report

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10.1016/j.amjmed.2021.03.028Licence: In Copyright

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title = "Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria",

abstract = "To the Editor:Hypovolemia is a well-recognized phenotype in patients with postural tachycardia syndrome. Previous work has identified paradoxical low renin-aldosterone levels and red blood cell deficit as indicators of a potential renal cause for postural tachycardia syndrome. Here we present the first published report of postural tachycardia syndrome exacerbation due to partial central diabetes insipidus (pCDI)-related polyuria and hypovolemia, and successful treatment following chronic desmopressin (DDAVP) therapy.",

keywords = "postural tachycardia syndrome, case report",

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AU - Seeley, Marie Claire

AU - Thynne, Tilenka R.

AU - Braund, Wilton J.

AU - Worthley, Daniel L.

AU - Gallagher, Celine

AU - Sanders, Prashanthan

AU - Lau, Dennis H.

PY - 2021/9

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AB - To the Editor:Hypovolemia is a well-recognized phenotype in patients with postural tachycardia syndrome. Previous work has identified paradoxical low renin-aldosterone levels and red blood cell deficit as indicators of a potential renal cause for postural tachycardia syndrome. Here we present the first published report of postural tachycardia syndrome exacerbation due to partial central diabetes insipidus (pCDI)-related polyuria and hypovolemia, and successful treatment following chronic desmopressin (DDAVP) therapy.

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KW - case report

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SP - e486-e487

JO - American Journal of Medicine

JF - American Journal of Medicine

IS - 9

ER -

Desmopressin as a Novel Long-Term Treatment in Postural Tachycardia Syndrome Patients with Polyuria

Abstract

Keywords

UN SDGs

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