Developing a Model of Care for Home Infusions of Natalizumab for People with Multiple Sclerosis

Timothy J. Schultz, Anne Thomas, Paul Georgiou, Lynette Cusack, Mahasen Juaton, Lorraine Simon, Kerisha Naidoo, Kevin Webb, Jonathan Karnon, Janakan Ravindran

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)
136 Downloads (Pure)


Natalizumab is an effective treatment for multiple sclerosis that requires 4-weekly infusions that are usually provided in hospital outpatient clinics. In this study, a model of care (MOC), an overarching design for the provision of a health care service, was developed to permit home infusions of natalizumab. The proposed new MOC comprised 9 dimensions, in addition to the central concept of patient-centered care at home. The new MOC is responsive to patient needs and prioritizes the nurse-patient therapeutic relationship. It provides practical examples of patient-centered care to guide clinical practice for this patient population in the home setting.

Original languageEnglish
Pages (from-to)289-296
Number of pages8
JournalJournal of Infusion Nursing
Issue number6
Publication statusPublished - 1 Nov 2019

Bibliographical note

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.


  • home care
  • home infusion therapy
  • model of care
  • multiple sclerosis
  • natalizumab
  • patient-centered care


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