Abstract
The use of X chromosomal short tandem repeat (STR) markers has been greatly increasing in the forensic setting. Using guidelines set forth previously for the validation of autosomal and Y STRs, aspects of the feasibility of routine X chromosomal STR use were evaluated. Two mini-X chromosomal STR multiplexes capable of amplifying 15 total markers were developed and utilized to determine allele nomenclature, allele/genotype frequencies, mutation rates, and linkage between markers. Additionally, a concordance study between these multiplexes and a commercially available kit was performed. Here, the authors present an overview of this extensive developmental validation study.
Original language | English |
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Pages | e142-e143 |
DOIs | |
Publication status | Published - 30 Oct 2013 |
Event | 25th World Congress of the International Society for Forensic Genetics - Melbourne, Australia Duration: 2 Sept 2013 → 7 Sept 2013 Conference number: 25 |
Conference
Conference | 25th World Congress of the International Society for Forensic Genetics |
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Abbreviated title | ISFG 2013 |
Country/Territory | Australia |
City | Melbourne |
Period | 2/09/13 → 7/09/13 |
Keywords
- Linkage
- Multiplex development
- Mutation rate
- Population database
- Short tandem repeat
- X chromosome