Differential attraction and repulsion of Staphylococcus aureus and Pseudomonas aeruginosa on molecularly smooth titanium films

Elena P. Ivanova, Vi Khanh Truong, Hayden K. Webb, Vladimir A. Baulin, James Y. Wang, Narges Mohammodi, Feng Wang, Christopher Fluke, Russell J. Crawford

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)

Abstract

Magnetron sputtering techniques were used to prepare molecularly smooth titanium thin films possessing an average roughness between 0.18 nm and 0.52 nm over 5 μm × 5 μm AFM scanning areas. Films with an average roughness of 0.52 nm or lower were found to restrict the extent of P. aeruginosa cell attachment, with less than 0.5% of all available cells being retained on the surface. The attachment of S. aureus cells was also limited on films with an average surface roughness of 0.52 nm, however they exhibited a remarkable propensity for attachment on the nano-smoother 0.18 nm average surface roughness films, with the attachment density being almost twice as great as that observed on the nano-rougher film. The difference in attachment behaviour can be attributed to the difference in morphology of the rod-shaped P. aeruginosa compared to the spherical S. aureus cells.

Original languageEnglish
Article number165
Number of pages8
JournalScientific Reports
Volume1
DOIs
Publication statusPublished - 22 Nov 2011
Externally publishedYes

Fingerprint

Dive into the research topics of 'Differential attraction and repulsion of Staphylococcus aureus and Pseudomonas aeruginosa on molecularly smooth titanium films'. Together they form a unique fingerprint.

Cite this