Digital PCR: A brief history

Alexander A. Morley

doi:10.1016/j.bdq.2014.06.001

Digital PCR: A brief history

Alexander A. Morley

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Abstract

Digital PCR for quantification of a target of interest has been independently developed several times, being described in 1990 and 1991 using the term "limiting dilution PCR" and in 1999 using the term "digital PCR". It came into use in the decade following its first development but its use was cut short by the description of real-time PCR in 1996. However digital PCR has now had a renaissance due to the recent development of new instruments and chemistry which have made it a much simpler and more practical technique.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Biomolecular Detection and Quantification
Volume	1
Issue number	1
DOIs	https://doi.org/10.1016/j.bdq.2014.06.001
Publication status	Published - Sept 2014

Bibliographical note

Open access under CC BY-NC-ND license.

Keywords

Digital PCR
Limiting dilution
PCR

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Published versionFinal published version, 219 KBLicence: CC BY-NC-ND

Cite this

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Digital PCR: A brief history

Abstract

Bibliographical note

Keywords

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