Does location of positive surgical margins after radical prostatectomy matter?—A systematic review and network meta-analysis

Athul John; Thomas Milton; Aashray Gupta; Mau Nguyen; Brandon Stretton; Joseph Hewitt; Rick Catterwell; Luke Selth; Michael O'Callaghan

doi:10.1111/iju.15019

Does location of positive surgical margins after radical prostatectomy matter?—A systematic review and network meta-analysis

Athul John, Thomas Milton, Aashray Gupta, Mau Nguyen, Brandon Stretton, Joseph Hewitt, Rick Catterwell, Luke Selth, Michael O'Callaghan

Research output: Contribution to journal › Meeting Abstract › peer-review

Abstract

Introduction and objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given its inconsistent predictive capacity for biochemical recurrence (BCR) and other outcomes. Recently, several studies have explored the location of positive surgical margins and their ability to predict BCR. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

Original language	English
Pages (from-to)	13-14
Number of pages	2
Journal	International Journal of Urology
Volume	29
Issue number	S1
Early online date	23 Sept 2022
DOIs	https://doi.org/10.1111/iju.15019
Publication status	Published - Oct 2022
Externally published	Yes
Event	19th Urological Association of Asia (UAA) Congress: Leading Urology through Converging Asian Insight - Sydney, Australia Duration: 5 Oct 2022 → 8 Oct 2022 Conference number: 29

Keywords

Radical prostatectomy
Biochemical recurrence
Positive surgical margin

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title = "Does location of positive surgical margins after radical prostatectomy matter?—A systematic review and network meta-analysis",

abstract = "Introduction and objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given its inconsistent predictive capacity for biochemical recurrence (BCR) and other outcomes. Recently, several studies have explored the location of positive surgical margins and their ability to predict BCR. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?",

keywords = "Radical prostatectomy, Biochemical recurrence, Positive surgical margin",

author = "Athul John and Thomas Milton and Aashray Gupta and Mau Nguyen and Brandon Stretton and Joseph Hewitt and Rick Catterwell and Luke Selth and Michael O'Callaghan",

year = "2022",

month = oct,

doi = "10.1111/iju.15019",

language = "English",

volume = "29",

pages = "13--14",

journal = "International Journal of Urology",

issn = "0919-8172",

publisher = "John Wiley & Sons, Inc",

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note = "19th Urological Association of Asia (UAA) Congress : Leading Urology through Converging Asian Insight, UAA 2022 ; Conference date: 05-10-2022 Through 08-10-2022",

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TY - JOUR

T1 - Does location of positive surgical margins after radical prostatectomy matter?—A systematic review and network meta-analysis

AU - John, Athul

AU - Milton, Thomas

AU - Gupta, Aashray

AU - Nguyen, Mau

AU - Stretton, Brandon

AU - Hewitt, Joseph

AU - Catterwell, Rick

AU - Selth, Luke

AU - O'Callaghan, Michael

N1 - Conference code: 29

PY - 2022/10

Y1 - 2022/10

N2 - Introduction and objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given its inconsistent predictive capacity for biochemical recurrence (BCR) and other outcomes. Recently, several studies have explored the location of positive surgical margins and their ability to predict BCR. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

AB - Introduction and objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given its inconsistent predictive capacity for biochemical recurrence (BCR) and other outcomes. Recently, several studies have explored the location of positive surgical margins and their ability to predict BCR. Hence, we aimed to systematically review and perform a network meta-analysis answering the clinical question: Does the location of PSM (Comparator and Intervention) influence the risk of BCR (Outcomes) in men with PSM after RP (Population)?

KW - Radical prostatectomy

KW - Biochemical recurrence

KW - Positive surgical margin

U2 - 10.1111/iju.15019

DO - 10.1111/iju.15019

M3 - Meeting Abstract

SN - 0919-8172

VL - 29

SP - 13

EP - 14

JO - International Journal of Urology

JF - International Journal of Urology

IS - S1

T2 - 19th Urological Association of Asia (UAA) Congress

Y2 - 5 October 2022 through 8 October 2022

ER -

Does location of positive surgical margins after radical prostatectomy matter?—A systematic review and network meta-analysis

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Keywords

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