Does size matter? Extension of positive surgical margins after radical prostatectomy – a systematic review and meta-analysis

A John; A Lim; R Catterwell; L Seth; M O'Callaghan

doi:10.1016/S0302-2838(22)00252-4

Does size matter? Extension of positive surgical margins after radical prostatectomy – a systematic review and meta-analysis

A John, A Lim, R Catterwell, L Seth, M O'Callaghan

College of Medicine and Public Health

Research output: Contribution to journal › Meeting Abstract › peer-review

Abstract

Introduction & Objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the extension of positive surgical margins and its ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a meta-analysis answering the clinical question: Does the size of PSM (Comparator and Intervention) influence BCR (Outcomes) in men with PSM after RP (Population)?

Original language	English
Article number	A0165
Pages (from-to)	S258
Number of pages	1
Journal	European Urology
Volume	81
Issue number	S1
DOIs	https://doi.org/10.1016/S0302-2838(22)00252-4
Publication status	Published - Feb 2022
Event	37th Annual European Association of Urology Congress - Amsterdam, Netherlands Duration: 1 Jul 2022 → 4 Jul 2022

Keywords

Positive surgical margins
Radical prostatectomy
Biochemical recurrence

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title = "Does size matter? Extension of positive surgical margins after radical prostatectomy – a systematic review and meta-analysis",

abstract = "Introduction & Objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the extension of positive surgical margins and its ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a meta-analysis answering the clinical question: Does the size of PSM (Comparator and Intervention) influence BCR (Outcomes) in men with PSM after RP (Population)?",

keywords = "Positive surgical margins, Radical prostatectomy, Biochemical recurrence",

author = "A John and A Lim and R Catterwell and L Seth and M O'Callaghan",

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TY - JOUR

T1 - Does size matter? Extension of positive surgical margins after radical prostatectomy – a systematic review and meta-analysis

AU - John, A

AU - Lim, A

AU - Catterwell, R

AU - Seth, L

AU - O'Callaghan, M

PY - 2022/2

Y1 - 2022/2

N2 - Introduction & Objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the extension of positive surgical margins and its ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a meta-analysis answering the clinical question: Does the size of PSM (Comparator and Intervention) influence BCR (Outcomes) in men with PSM after RP (Population)?

AB - Introduction & Objectives: The relevance of positive surgical margins (PSM) in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given that its prognostic capacity for biochemical recurrence (BCR) and other outcomes is inconsistent. Over the last decade, several studies have explored the extension of positive surgical margins and its ability to predict biochemical recurrence. Hence, we aimed to systematically review and perform a meta-analysis answering the clinical question: Does the size of PSM (Comparator and Intervention) influence BCR (Outcomes) in men with PSM after RP (Population)?

KW - Positive surgical margins

KW - Radical prostatectomy

KW - Biochemical recurrence

U2 - 10.1016/S0302-2838(22)00252-4

DO - 10.1016/S0302-2838(22)00252-4

M3 - Meeting Abstract

SN - 0302-2838

VL - 81

SP - S258

JO - European Urology

JF - European Urology

IS - S1

M1 - A0165

T2 - 37th Annual European Association of Urology Congress

Y2 - 1 July 2022 through 4 July 2022

ER -

Does size matter? Extension of positive surgical margins after radical prostatectomy – a systematic review and meta-analysis

Abstract

Keywords

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