TY - JOUR
T1 - Driving innovation through collaboration
T2 - Development of clinical annotation datasets for brain cancer biobanking
AU - Gedye, Craig
AU - Sachchithananthan, Mythily
AU - Leonard, Robyn
AU - Jeffree, Rosalind L.
AU - Buckland, Michael E.
AU - Ziegler, David S.
AU - Graeber, Manuel B.
AU - Day, Bryan W.
AU - McDonald, Kerrie L.
AU - Lasocki, Arian
AU - BCBA Consortium
AU - Back, Michael
AU - Besser, Michael
AU - Boyd, Andrew
AU - Byrne, Jennifer
AU - Cher, Lawrence
AU - Cook, Raymond
AU - Day, Jerry
AU - Davidson, Andrew
AU - Devereux, Lisa
AU - Dexter, Mark
AU - Donnelly, Roy
AU - Drummond, Kate
AU - Eckstein, Lisa
AU - Gan, Hui
AU - Garrick, Therese
AU - Gottardo, Nick
AU - Harper, Clive
AU - Johns, Terrance
AU - Khasraw, Mustafa
AU - Kichenadasse, Ganessan
AU - Eng-Siew, Koh
AU - Lipworth, Wendy
AU - Ludlow, Louise
AU - Moore, Andrew
AU - Munoz, Lenka
AU - Nahar, Najmun
AU - Olson, Sarah
AU - Ormsby, Rebecca
AU - Parkinson, Jonathon
AU - Partanen, Audrey
AU - Raymond, Emma
AU - Reddel, Roger
AU - Robbins, Peter
AU - Rosenthal, Mark
AU - Saunus, Jodi
AU - Shivalingam, Brindha
AU - Simes, John
AU - Stringer, Brett
AU - Thorne, Heather
AU - Vajdic, Claire
AU - Varikatt, Winny
AU - Walker, David
AU - Wheeler, Helen
AU - White, Deborah
AU - Yip, Sonia
AU - Nowak, Anna K.
PY - 2020/2
Y1 - 2020/2
N2 - Background: A key component of cancer research is the availability of clinical samples with appropriately annotated clinical data. Biobanks facilitate research by collecting/storing various types of clinical samples for research. Brain Cancer Biobanking Australia (BCBA) was established to facilitate the networking of brain cancer biobanking operations Australia-wide. Maximizing biospecimen utility in a networked biobanking environment requires the standardization of procedures and data across different sites. The aim of this research was to scope and develop a recommended clinical annotation dataset both for pediatric and adult brain cancer biobanks. Methods: A multidisciplinary working group consisting of members from the BCBA Consortium was established to develop clinical dataset recommendations for brain cancer biobanks. A literature search was undertaken to identify any published clinical dataset recommendations for brain cancer biobanks. An audit of data items collected and stored by BCBA member biobanks was also conducted to survey current clinical data collection practices across the BCBA network. Results: BCBA has developed a clinical annotation dataset recommendation for pediatric and adult brain cancer biobanks. The clinical dataset recommendation has 5 clinical data categories: demographic, clinical and radiological diagnosis and surgery, neuropathological diagnosis, patient treatment, and patient follow-up. The data fields have been categorized into 1 of 3 tiers; essential, preferred, and comprehensive. This enables biobanks and researchers to prioritize appropriately where resources are limited. Conclusion: This dataset can be used to guide the integration of data from multiple existing biobanks for research studies and for planning prospective brain cancer biobanking activities.
AB - Background: A key component of cancer research is the availability of clinical samples with appropriately annotated clinical data. Biobanks facilitate research by collecting/storing various types of clinical samples for research. Brain Cancer Biobanking Australia (BCBA) was established to facilitate the networking of brain cancer biobanking operations Australia-wide. Maximizing biospecimen utility in a networked biobanking environment requires the standardization of procedures and data across different sites. The aim of this research was to scope and develop a recommended clinical annotation dataset both for pediatric and adult brain cancer biobanks. Methods: A multidisciplinary working group consisting of members from the BCBA Consortium was established to develop clinical dataset recommendations for brain cancer biobanks. A literature search was undertaken to identify any published clinical dataset recommendations for brain cancer biobanks. An audit of data items collected and stored by BCBA member biobanks was also conducted to survey current clinical data collection practices across the BCBA network. Results: BCBA has developed a clinical annotation dataset recommendation for pediatric and adult brain cancer biobanks. The clinical dataset recommendation has 5 clinical data categories: demographic, clinical and radiological diagnosis and surgery, neuropathological diagnosis, patient treatment, and patient follow-up. The data fields have been categorized into 1 of 3 tiers; essential, preferred, and comprehensive. This enables biobanks and researchers to prioritize appropriately where resources are limited. Conclusion: This dataset can be used to guide the integration of data from multiple existing biobanks for research studies and for planning prospective brain cancer biobanking activities.
KW - biobanking
KW - brain cancer
KW - clinical annotation
KW - datasets
KW - neuro-oncology
UR - http://www.scopus.com/inward/record.url?scp=85085169486&partnerID=8YFLogxK
U2 - 10.1093/nop/npz036
DO - 10.1093/nop/npz036
M3 - Article
AN - SCOPUS:85085169486
SN - 2054-2577
VL - 7
SP - 31
EP - 37
JO - Neuro-Oncology Practice
JF - Neuro-Oncology Practice
IS - 1
ER -
