Drug Burden Index in older adults: theoretical and practical issues

Lisa Kouladjian; Danijela Gnjidic; Timothy Chen; Arduino Mangoni; Sarah Hilmer

doi:10.2147/CIA.S66660

Drug Burden Index in older adults: theoretical and practical issues

Lisa Kouladjian, Danijela Gnjidic, Timothy Chen, Arduino Mangoni, Sarah Hilmer

Research output: Contribution to journal › Review article › peer-review

121 Citations (Scopus)

Abstract

Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.

Original language	English
Pages (from-to)	1503-1515
Number of pages	13
Journal	Clinical Interventions in Aging
Volume	9
DOIs	https://doi.org/10.2147/CIA.S66660
Publication status	Published - 9 Sept 2014

Keywords

Anticholinergics
Deprescribing
Drug burden index
High-risk prescribing
Older adults
Pharmacological risk assessment tools
Sedative medications

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KW - Deprescribing

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KW - Older adults

KW - Pharmacological risk assessment tools

KW - Sedative medications

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JF - Clinical Interventions in Aging

ER -

Drug Burden Index in older adults: theoretical and practical issues

Abstract

Keywords

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