Drug-induced Acute Pancreatitis – ‘Scope for Secondary Prevention’.

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I read with interest the article by Chang et al. [1] in which the authors adopt a systematic approach (including taking into account binary clinical conditions such as the presence of hypertriglyceridemia, alcohol and / or tobacco use, gall-stone, obesity and bilio-pancreatic cancers, estimating dose response effects and performing sensitivity analyses) to tease out the relationship of various anti-diabetic drugs and the risk of Acute pancreatitis (AP). In the end, they provide compelling evidence that sulfonylureas carry a more signifi-cant risk of causing AP compared to metformin which in turn carry a more significant risk that dipeptidyl peptidase-4.
Original languageEnglish
Article number019
Number of pages2
JournalJacobs Journal of Gastroenterology and Hepatology
Issue number4
Publication statusPublished - Oct 2016
Externally publishedYes


  • Acute pancreatitis
  • Disease prevention
  • Prescriptions
  • Medication


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