Dynamics of the human upper airway: On the development of a three-dimensional computational model

J. Wang, G. A. Tetlow, A. D. Lucey, J. J. Armstrong, Matthew S. Leigh, Alexandre Paduch, David D. Sampson, J. H. Walsh, P. R. Eastwood, D. R. Hillman, S. Harrison

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

The advances reported herein form part of a larger project that has as its objective the development of a full flow-structure-interaction model of the human upper airway. Here we first briefly report on a two-dimensional (saggital section) model built using published CT-scan geometric data. For the development of our three-dimensional capability, we use the unique data captured in vivo by an endoscopic optical technique that we have developed. This measurement system, described as anatomical optical coherence tomography (aOCT), allows quantitative real-time imaging of the internal anatomy of the human upper airway with minimal invasiveness. Moreover, the system permits motions of the internal geometry at a fixed location to be recorded. The aOCT data set is insufficient by itself to construct a complete geometry because only the polar coordinates are obtained in a local reference frame. Accordingly, the locus described by the endoscope, in which the aOCT is housed, is obtained by orthogonal CT scans. The combination of CT scans and aOCT measurements then provides the required geometric information for the construction of the computational model. Results of a twodimensional model show how the soft palate responds to the mean-flow variations of the breathing cycle. For the threedimensional work, the key results of this paper rest in the reconstruction of the time-dependent geometry of the upper airway, the first time that this has been accomplished using direct internally-based measurement.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering 2006
Subtitle of host publicationIFMBE Proceedings
EditorsR. Magjarevic, J. H. Nagel
PublisherSpringer-Verlag
Pages3449-3452
Number of pages4
Volume14
ISBN (Electronic)978-3-540-36841-0
ISBN (Print)9783540368397
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 27 Aug 20061 Sep 2006

Publication series

NameIFMBE Proceedings
Number1
Volume14
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Conference

Conference10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/TerritoryKorea, Republic of
CitySeoul
Period27/08/061/09/06

Bibliographical note

Publisher Copyright:
© International Federation for Medical and Biological Engineering 2007.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

  • CAD modeling
  • Image processing
  • Sleep apnea
  • Upper-airway anatomy
  • Upperairway modeling

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