TY - JOUR
T1 - Eating disorder outcomes
T2 - findings from a rapid review of over a decade of research
AU - Miskovic-Wheatley, Jane
AU - Bryant, Emma
AU - Ong, Shu Hwa
AU - Vatter, Sabina
AU - Le, Anvi
AU - National Eating Disorder Research Consortium
AU - Aouad, Phillip
AU - Barakat, Sarah
AU - Boakes, Robert
AU - Brennan, Leah
AU - Byrne, Susan
AU - Caldwell, Belinda
AU - Calvert, Shannon
AU - Carroll, Bronny
AU - Castle, David
AU - Caterson, Ian
AU - Chelius, Belinda
AU - Chiem, Lyn
AU - Clarke, Simon
AU - Conti, Janet
AU - Crouch, Lexi
AU - Dammery, Genevieve
AU - Dzajkovski, Natasha
AU - Fardouly, Jasmine
AU - Felicia, Carmen
AU - Feneley, John
AU - Firriolo, Amber Marie
AU - Foroughi, Nasim
AU - Fuller-Tyszkiewicz, Mathew
AU - Fursland, Anthea
AU - Gonzalez-Arce, Veronica
AU - Gouldthorp, Bethanie
AU - Griffin, Kelly
AU - Griffiths, Scott
AU - Hambleton, Ashlea
AU - Hannigan, Amy
AU - Hart, Mel
AU - Hart, Susan
AU - Hay, Phillipa
AU - Hickie, Ian
AU - Kay-Lambkin, Francis
AU - King, Ross
AU - Kohn, Michael
AU - Koreshe, Eyza
AU - Krug, Isabel
AU - Linardon, Jake
AU - Long, Randall
AU - Long, Amanda
AU - Madden, Sloane
AU - Maloney, Danielle
AU - Marks, Peta
AU - McLean, Sian
AU - Meddick, Thy
AU - Mitchison, Deborah
AU - O’Kearney, Richard
AU - Paterson, Roger
AU - Paxton, Susan
AU - Pehlivan, Melissa
AU - Pepin, Genevieve
AU - Phillipou, Andrea
AU - Piccone, Judith
AU - Pinkus, Rebecca
AU - Raykos, Bronwyn
AU - Rhodes, Paul
AU - Rieger, Elizabeth
AU - Rodan, Sarah Catherine
AU - Rockett, Karen
AU - Russell, Janice
AU - Russell, Haley
AU - Salter, Fiona
AU - Sawyer, Susan
AU - Shelton, Beth
AU - Singh, Urvashnee
AU - Smith, Sophie
AU - Smith, Evelyn
AU - Spielman, Karen
AU - Squire, Sarah
AU - Thomson, Juliette
AU - Utpala, Ranjani
AU - Vartanian, Lenny
AU - Wallis, Andrew
AU - Ward, Warren
AU - Wells, Sarah
AU - Wertheim, Eleanor
AU - Wilksch, Simon
AU - Williams, Michelle
AU - Touyz, Stephen
AU - Maguire, Sarah
PY - 2023/12
Y1 - 2023/12
N2 - Background: Eating disorders (ED), especially Anorexia Nervosa (AN), are internationally reported to have amongst the highest mortality and suicide rates in mental health. With limited evidence for current pharmacological and/or psychological treatments, there is a grave responsibility within health research to better understand outcomes for people with a lived experience of ED, factors and interventions that may reduce the detrimental impact of illness and to optimise recovery. This paper aims to synthesise the literature on outcomes for people with ED, including rates of remission, recovery and relapse, diagnostic crossover, and mortality. Methods: This paper forms part of a Rapid Review series scoping the evidence for the field of ED, conducted to inform the Australian National Eating Disorders Research and Translation Strategy 2021–2031, funded and released by the Australian Government. ScienceDirect, PubMed and Ovid/MEDLINE were searched for studies published between 2009 and 2022 in English. High-level evidence such as meta-analyses, large population studies and Randomised Controlled Trials were prioritised through purposive sampling. Data from selected studies relating to outcomes for people with ED were synthesised and are disseminated in the current review. Results: Of the over 1320 studies included in the Rapid Review, the proportion of articles focused on outcomes in ED was relatively small, under 9%. Most evidence was focused on the diagnostic categories of AN, Bulimia Nervosa and Binge Eating Disorder, with limited outcome studies in other ED diagnostic groups. Factors such as age at presentation, gender, quality of life, the presence of co-occurring psychiatric and/or medical conditions, engagement in treatment and access to relapse prevention programs were associated with outcomes across diagnoses, including mortality rates. Conclusion: Results are difficult to interpret due to inconsistent study definitions of remission, recovery and relapse, lack of longer-term follow-up and the potential for diagnostic crossover. Overall, there is evidence of low rates of remission and high risk of mortality, despite evidence-based treatments, especially for AN. It is strongly recommended that research in long-term outcomes, and the factors that influence better outcomes, using more consistent variables and methodologies, is prioritised for people with ED.
AB - Background: Eating disorders (ED), especially Anorexia Nervosa (AN), are internationally reported to have amongst the highest mortality and suicide rates in mental health. With limited evidence for current pharmacological and/or psychological treatments, there is a grave responsibility within health research to better understand outcomes for people with a lived experience of ED, factors and interventions that may reduce the detrimental impact of illness and to optimise recovery. This paper aims to synthesise the literature on outcomes for people with ED, including rates of remission, recovery and relapse, diagnostic crossover, and mortality. Methods: This paper forms part of a Rapid Review series scoping the evidence for the field of ED, conducted to inform the Australian National Eating Disorders Research and Translation Strategy 2021–2031, funded and released by the Australian Government. ScienceDirect, PubMed and Ovid/MEDLINE were searched for studies published between 2009 and 2022 in English. High-level evidence such as meta-analyses, large population studies and Randomised Controlled Trials were prioritised through purposive sampling. Data from selected studies relating to outcomes for people with ED were synthesised and are disseminated in the current review. Results: Of the over 1320 studies included in the Rapid Review, the proportion of articles focused on outcomes in ED was relatively small, under 9%. Most evidence was focused on the diagnostic categories of AN, Bulimia Nervosa and Binge Eating Disorder, with limited outcome studies in other ED diagnostic groups. Factors such as age at presentation, gender, quality of life, the presence of co-occurring psychiatric and/or medical conditions, engagement in treatment and access to relapse prevention programs were associated with outcomes across diagnoses, including mortality rates. Conclusion: Results are difficult to interpret due to inconsistent study definitions of remission, recovery and relapse, lack of longer-term follow-up and the potential for diagnostic crossover. Overall, there is evidence of low rates of remission and high risk of mortality, despite evidence-based treatments, especially for AN. It is strongly recommended that research in long-term outcomes, and the factors that influence better outcomes, using more consistent variables and methodologies, is prioritised for people with ED.
KW - Anorexia nervosa
KW - Binge eating disorder
KW - Bulimia nervosa
KW - Eating disorders
KW - Mortality
KW - Outcomes
KW - Recovery
KW - Relapse
KW - Remission
KW - Transdiagnostic
UR - http://www.scopus.com/inward/record.url?scp=85160918876&partnerID=8YFLogxK
U2 - 10.1186/s40337-023-00801-3
DO - 10.1186/s40337-023-00801-3
M3 - Article
AN - SCOPUS:85160918876
SN - 2050-2974
VL - 11
JO - Journal of Eating Disorders
JF - Journal of Eating Disorders
IS - 1
M1 - 85
ER -