EBNEO commentary: Foetal surgery for severe left diaphragmatic hernia

Beth Godden; Amy Keir

doi:10.1111/apa.16299

EBNEO commentary: Foetal surgery for severe left diaphragmatic hernia

Beth Godden, Amy Keir

Research output: Contribution to journal › Comment/debate

Abstract

Previous observational and small single centre randomised trials have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated left-sided congenital diaphragmatic hernia. The Tracheal Occlusion to Accelerate Lung Growth (TOTAL) trial, including the Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia and the Randomized Trial of Fetal Surgery for Moderate Left Diaphragmatic Hernia, was designed to test this hypothesis.

Original language	English
Pages (from-to)	1287-1288
Number of pages	2
Journal	Acta Paediatrica, International Journal of Paediatrics
Volume	111
Issue number	6
DOIs	https://doi.org/10.1111/apa.16299
Publication status	Published - Jun 2022
Externally published	Yes

Keywords

Fetal surgery
Diaphragmatic hernia
Randomised trials

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abstract = "Previous observational and small single centre randomised trials have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated left-sided congenital diaphragmatic hernia. The Tracheal Occlusion to Accelerate Lung Growth (TOTAL) trial, including the Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia and the Randomized Trial of Fetal Surgery for Moderate Left Diaphragmatic Hernia, was designed to test this hypothesis.",

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AU - Keir, Amy

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AB - Previous observational and small single centre randomised trials have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated left-sided congenital diaphragmatic hernia. The Tracheal Occlusion to Accelerate Lung Growth (TOTAL) trial, including the Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia and the Randomized Trial of Fetal Surgery for Moderate Left Diaphragmatic Hernia, was designed to test this hypothesis.

KW - Fetal surgery

KW - Diaphragmatic hernia

KW - Randomised trials

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UR - http://purl.org/au-research/grants/NHMRC/1161379

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M3 - Comment/debate

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JO - Acta Paediatrica, International Journal of Paediatrics

JF - Acta Paediatrica, International Journal of Paediatrics

IS - 6

ER -

EBNEO commentary: Foetal surgery for severe left diaphragmatic hernia

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