TY - JOUR
T1 - Editorial: Synovial tissue biopsy research
AU - Veale, Douglas J.
AU - Firestein, Gary S.
AU - Wechalekar, Mihir D.
AU - Najm, Aurélie
PY - 2022/10/4
Y1 - 2022/10/4
N2 - Rheumatoid arthritis (RA) is an inflammatory autoimmune disease, that left untreated results in pain, joint damage, and functional disability for the patients. In healthy persons, the synovium is a loose connective tissue with one or two cells lining the surface without a basement membrane. It adheres to the internal joint capsule, which is comprised of ligaments. In RA, the synovium expands with finger-like projections (villi) that are highly vascularised with new blood vessels and abundant activated immune cells including macrophages, lymphocytes, and resident stromal cells, i.e., fibroblasts and dendritic cells.
AB - Rheumatoid arthritis (RA) is an inflammatory autoimmune disease, that left untreated results in pain, joint damage, and functional disability for the patients. In healthy persons, the synovium is a loose connective tissue with one or two cells lining the surface without a basement membrane. It adheres to the internal joint capsule, which is comprised of ligaments. In RA, the synovium expands with finger-like projections (villi) that are highly vascularised with new blood vessels and abundant activated immune cells including macrophages, lymphocytes, and resident stromal cells, i.e., fibroblasts and dendritic cells.
KW - rheumatoid arthritis
KW - Psoriatic arthritis
KW - synovial tissue
KW - biopsies
KW - cellular and molecular analysis
UR - http://www.scopus.com/inward/record.url?scp=85140582498&partnerID=8YFLogxK
U2 - 10.3389/fmed.2022.1004029
DO - 10.3389/fmed.2022.1004029
M3 - Editorial
SN - 2296-858X
VL - 9
JO - Frontiers in Medicine
JF - Frontiers in Medicine
M1 - 1004029
ER -