Effect of age on sensitivity of human lymphocytes to radiation. A brief note

R. Kutlaca; R. Seshadri; A. A. Morley

doi:10.1016/0047-6374(82)90001-X

Effect of age on sensitivity of human lymphocytes to radiation. A brief note

R. Kutlaca, R. Seshadri, A. A. Morley

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28 Citations (Scopus)

Abstract

Survival of human lymphocytes after X-ray and ultraviolet irradiation was studied in individuals of various ages using a technique of cloning in soft agar. There was no effect of age on survival after ultraviolet irradiation but lymphocytes from elderly individuals were approximately twice as sensitive to X-radiation as lymphocytes from young individuals. The results are relevant to the possible importance of DNA damage and repair in cellular ageing.

Original language	English
Pages (from-to)	97-101
Number of pages	5
Journal	Mechanisms of Ageing and Development
Volume	19
Issue number	2
DOIs	https://doi.org/10.1016/0047-6374(82)90001-X
Publication status	Published - Jun 1982
Externally published	Yes

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abstract = "Survival of human lymphocytes after X-ray and ultraviolet irradiation was studied in individuals of various ages using a technique of cloning in soft agar. There was no effect of age on survival after ultraviolet irradiation but lymphocytes from elderly individuals were approximately twice as sensitive to X-radiation as lymphocytes from young individuals. The results are relevant to the possible importance of DNA damage and repair in cellular ageing.",

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AB - Survival of human lymphocytes after X-ray and ultraviolet irradiation was studied in individuals of various ages using a technique of cloning in soft agar. There was no effect of age on survival after ultraviolet irradiation but lymphocytes from elderly individuals were approximately twice as sensitive to X-radiation as lymphocytes from young individuals. The results are relevant to the possible importance of DNA damage and repair in cellular ageing.

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Effect of age on sensitivity of human lymphocytes to radiation. A brief note

Abstract

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