Effect of dietary copper on the growth performance, non-specific immunity and resistance to Aeromonas hydrophila of juvenile Chinese mitten crab, Eriocheir sinensis

Shengming Sun, Jianguang Qin, Liqiao Chen, XP Ge, Haibo Jiang

    Research output: Contribution to journalArticle

    42 Citations (Scopus)

    Abstract

    An 8-week feeding trial was conducted to determine the dietary copper (Cu) on growth performance and immune responses of juvenile Chinese mitten crab Eriocheir sinensis. Six semi-purified diets with six copper levels (1.88, 11.85, 20.78, 40.34, 79.56 and 381.2 mg kg-1 diet) of CuSO4·5H2O were fed to E. sinensis (0.45 ± 0.01 g). Each diet was fed to the crab in five replicates. The crab fed diets with 20.78 and 40.34 mg Cu kg-1 diet had significantly greater weight gain and hemolymph oxyhemocyanin content than those fed diets with 1.88 and 381.2 mg Cu kg-1 diet. Survival rates of crab were not significantly different between all treatment groups. The activities of copper-zinc superoxide dismutase (Cu-Zn SOD), phenoloxidase (PO), and total hemocyte count (THC) significantly increased when the supplementation of dietary copper reached 20.78-40.34 mg Cu kg-1 diets. In the bacteria challenge experiment with Aeromonas hydrophila, survival rates significantly increased and reached a plateau when the dietary copper increased from 1.88 to 40.34 mg kg-1, whereas significantly decreased when the dietary copper increased from 40.34 to 381.2 mg kg-1. This study indicates that the level of dietary copper is important in regulating growth and immune response in crab.

    Original languageEnglish
    Pages (from-to)1195-1201
    Number of pages7
    JournalFish and Shellfish Immunology
    Volume34
    Issue number5
    DOIs
    Publication statusPublished - May 2013

    Keywords

    • Copper
    • Eriocheir sinensis
    • Growth
    • Non-specific immunity
    • Oxyhemocyanin

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