Effect Of High-intensity Interval Training On Insulin Quality In Participants With Metabolic Syndrome

Joyce Ramos, Lance Dalleck, Fabio Borrani, Roger G. Fassett, Shelley E. Keating, Jeff Coombes

Research output: Contribution to journalMeeting Abstractpeer-review

Abstract

The continuous demand for insulin in the face of insulin resistance, coupled with the glucolipotoxic environment associated with the metabolic syndrome (MetS), adversely affects the ‘quality’ of insulin produced and secreted by the pancreatic beta cells. This is depicted by increased circulating intact proinsulin concentration (IPC) which is associated with increased MetS severity and risk of cardiovascular (CV) mortality. High-intensity interval training (HIIT) has been shown to reduce insulin resistance and other cardiovascular disease risk factors to a greater degree than moderate-intensity continuous training (MICT)
Original languageEnglish
Pages (from-to)642
Number of pages1
JournalMedicine and Science in Sports and Exercise
Volume48
Issue number5S
DOIs
Publication statusPublished - May 2016
Externally publishedYes
EventAmerican College of Sports Medicine, 2016 - Boston, United States
Duration: 31 May 20164 Jun 2016

Keywords

  • High-intensity interval training
  • insulin quality
  • metabolic syndrome
  • insulin resistance
  • glucolipotoxic
  • Pancreatic beta cell function
  • intact proinsulin concentration (IPC)

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