Abstract
The continuous demand for insulin in the face of insulin resistance, coupled with the glucolipotoxic environment associated with the metabolic syndrome (MetS), adversely affects the ‘quality’ of insulin produced and secreted by the pancreatic beta cells. This is depicted by increased circulating intact proinsulin concentration (IPC) which is associated with increased MetS severity and risk of cardiovascular (CV) mortality. High-intensity interval training (HIIT) has been shown to reduce insulin resistance and other cardiovascular disease risk factors to a greater degree than moderate-intensity continuous training (MICT)
Original language | English |
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Pages (from-to) | 642 |
Number of pages | 1 |
Journal | Medicine and Science in Sports and Exercise |
Volume | 48 |
Issue number | 5S |
DOIs | |
Publication status | Published - May 2016 |
Externally published | Yes |
Event | American College of Sports Medicine, 2016 - Boston, United States Duration: 31 May 2016 → 4 Jun 2016 |
Keywords
- High-intensity interval training
- insulin quality
- metabolic syndrome
- insulin resistance
- glucolipotoxic
- Pancreatic beta cell function
- intact proinsulin concentration (IPC)