Effect of multidisciplinary rehabilitation on sleep outcomes in individuals with preclinical Huntington disease: An exploratory study

Danielle M. Bartlett, Govinda Poudel, Kathleen J. Maddison, Amit Lampit, Linda Dann, Peter Eastwood, Alpar S. Lazar, Mel R. Ziman, Travis M. Cruickshank

Research output: Contribution to journalLetter

2 Citations (Scopus)

Abstract

Dear Editor. Sleep disturbances are an early feature of Huntington disease(HD), which worsen as the disease progresses. Studies have documented increased sleep fragmentation, decreased rapid eye-movement (REM) sleep, reduced sleep efficiency, insomnia and an increase in periodic leg movements (PLMs) in individuals with HD [1,2]. Disturbances in sleep are thought to exacerbate cognitive impairments and may hasten subcortical neurodegeneration [3,4]. Hence, management of sleep disturbances in individuals with HD is imperative...
Original languageEnglish
Pages (from-to)570-573
Number of pages4
JournalAnnals of Physical and Rehabilitation Medicine
Volume63
Issue number6
Early online date25 Nov 2020
DOIs
Publication statusPublished - Nov 2020
Externally publishedYes

Keywords

  • Huntington disease
  • sleep disorders
  • sleep fragmentation
  • periodic leg movements (PLMs)

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