Effectiveness of cardiac rehabilitation programs versus standard care on medication adherence in patients with cardiovascular disease: A systematic review protocol

Research output: Contribution to journalReview articlepeer-review

Abstract

Objective:
The objective of this review is to measure the effectiveness of cardiac rehabilitation programs versus standard care on medication adherence in patients with cardiovascular disease.

Introduction:
Poor adherence to long-term medications increases the risk of morbidity and mortality, and decreases quality of life in patients with cardiovascular diseases. Several strategies have been trialed to improve medication adherence in patients with cardiovascular disease, one of which is cardiac rehabilitation programs. Although evidence has indicated that cardiac rehabilitation programs increase medication adherence, the extent of its effectiveness and translation into clinical practice is not well documented. Our systematic review will collect and analyze the available evidence for clinical practice implementation.

Inclusion criteria:
The search will aim to locate randomized controlled trials. Where randomized controlled trials are not available, quasi-experimental studies, case-control studies, observational studies, and other study designs will be included to meet the objective of the study. Studies that measure effectiveness of cardiac rehabilitation programs compared to standard care on medication adherence in cardiovascular disease patients will be included.

Methods:
Databases, including MEDLINE (Ovid), Emcare (Ovid), Embase (Ovid), Cochrane CENTRAL, Scopus (Elsevier), CINAHL (EBSCO), and unpublished sources will also be searched. Articles in English and non-English-language articles with an English-language abstract published from database inception to the present will be included. Articles will be screened and reviewed by two independent reviewers for inclusion. Critical appraisal tools will be applied to the included studies. Data will be extracted using the appropriate extraction tools and synthesized for the objectives of the study.

Systematic review registration number:
PROSPERO CRD42021284705
Original languageEnglish
Number of pages8
JournalJBI Evidence Synthesis
DOIs
Publication statusAccepted/In press - 11 Jul 2022

Keywords

  • cardiac rehabilitation
  • medication adherence
  • effectiveness
  • Standard care
  • Systematic review

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