Effects of clozapine for non-treatment-resistant patients with schizophrenia

Cherrie A. Galletly; C. Richard Clark; Alexander C. McFarlane; Darren L. Weber

doi:10.1176/ps.50.1.101

Effects of clozapine for non-treatment-resistant patients with schizophrenia

Cherrie A. Galletly, C. Richard Clark, Alexander C. McFarlane, Darren L. Weber

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Clozapine is generally used for patients meeting criteria for treatment resistance. In this study clozapine was given to 19 patients with schizophrenia who did not meet these criteria and whose symptoms were mild to moderate in severity. Clozapine was associated with significant improvement in positive and negative symptoms and quality of life. A more modest improvement on a range of tests of cognitive functioning was also noted. These results suggest that consideration should be given to broadening the usual criteria for patients' eligibility for clozapine treatment.

Original language	English
Pages (from-to)	101-103
Number of pages	3
Journal	Psychiatric Services
Volume	50
Issue number	1
DOIs	https://doi.org/10.1176/ps.50.1.101
Publication status	Published - Jan 1999

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Effects of clozapine for non-treatment-resistant patients with schizophrenia

Abstract

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