Effects of olfactory bulb lesions on brain monoamines

L. A. Pohorecky, J. P. Chalmers

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Unilateral olfactory bulb lesions in the rat caused a selective decrease and increase of norepinephrine in the telencephalon and the brainstem, respectively. There were no changes in the concentration of dopamine or serotonin in the ipsilateral telencephalon or brainstem of rats with unilateral lesions. The increase in brainstem norepinephrine concentration in animals with olfactory bulb lesions was reduced when the animals were kept 5 to a cage post-operatively, rather than in isolation.

Original languageEnglish
Pages (from-to)985-998
Number of pages14
JournalLife Sciences
Issue number17, Part 1
Publication statusPublished - 1 Sep 1971
Externally publishedYes


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