In this work, we aimed to understand the key properties that confer antibacterial activity to chlorinated plasma polymers, by investigating plasma polymers deposited from a series of chlorinated precursor molecules and also investigating the effect of plasma conditions. Results revealed that only precursors with a Cl/C ratio ≥1.5 generate effective antibacterial coatings, whereas the coating thickness is irrelevant. Furthermore there is a “sweet spot” in process conditions to generate coatings with optimal antimicrobial activity. Lastly, we investigated the release of chlorinated fragments and attenuation of the surface-active antibacterial properties of the chlorinated plasma polymers by overcoating them with a perfluorinated plasma polymer.
- mechanism of action
- plasma polymer