Effects of Precursor and Deposition Conditions on Prevention of Bacterial Biofilm Growth on Chlorinated Plasma Polymers

Thomas D. Michl, Bryan R. Coad, Amanda Hüsler, Jules D.P. Valentin, Krasimir Vasilev, Hans J. Griesser

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

In this work, we aimed to understand the key properties that confer antibacterial activity to chlorinated plasma polymers, by investigating plasma polymers deposited from a series of chlorinated precursor molecules and also investigating the effect of plasma conditions. Results revealed that only precursors with a Cl/C ratio ≥1.5 generate effective antibacterial coatings, whereas the coating thickness is irrelevant. Furthermore there is a “sweet spot” in process conditions to generate coatings with optimal antimicrobial activity. Lastly, we investigated the release of chlorinated fragments and attenuation of the surface-active antibacterial properties of the chlorinated plasma polymers by overcoating them with a perfluorinated plasma polymer.

Original languageEnglish
Pages (from-to)654-662
Number of pages9
JournalPlasma Processes and Polymers
Volume13
Issue number6
DOIs
Publication statusPublished - Jun 2016
Externally publishedYes

Keywords

  • antibacterial
  • chlorinated
  • coating
  • mechanism of action
  • plasma polymer

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