Efficacy of High-Dose, Rapid, Hepatitis A and B Vaccination Schedules in Patients With Cirrhosis

Alan J. Wigg; Rachel Wundke; Rosemary McCormick; Kate R. Muller; Jeyamani Ramachandran; Sumudu K. Narayana; Richard J. Woodman

doi:10.1016/j.cgh.2018.08.047

Efficacy of High-Dose, Rapid, Hepatitis A and B Vaccination Schedules in Patients With Cirrhosis

Alan J. Wigg, Rachel Wundke, Rosemary McCormick, Kate R. Muller, Jeyamani Ramachandran, Sumudu K. Narayana, Richard J. Woodman

College of Medicine and Public Health

Research output: Contribution to journal › Short survey › peer-review

12 Citations (Scopus)

Abstract

Patients with cirrhosis have increased morbidity from hepatitis A virus (HAV) and hepatitis B virus (HBV) infections, and vaccination against these infections is an important standard of care. ^1,2 However, vaccination in patients with cirrhosis is hindered by immune dysfunction and there is limited high-quality literature available. The aim of this work therefore was to compare immune responses of standard dose (SD) with high-dose accelerated (HDA) vaccination in cirrhotic patients.

Original language	English
Pages (from-to)	1210-1212.e1
Number of pages	3
Journal	Clinical Gastroenterology and Hepatology
Volume	17
Issue number	6
Early online date	23 Aug 2018
DOIs	https://doi.org/10.1016/j.cgh.2018.08.047
Publication status	Published - May 2019

Keywords

cirrhosis
Hepatitis A
Hepatitis B
Vaccination
Patient outcomes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cgh.2018.08.047Licence: In Copyright

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title = "Efficacy of High-Dose, Rapid, Hepatitis A and B Vaccination Schedules in Patients With Cirrhosis",

abstract = " Patients with cirrhosis have increased morbidity from hepatitis A virus (HAV) and hepatitis B virus (HBV) infections, and vaccination against these infections is an important standard of care. 1,2 However, vaccination in patients with cirrhosis is hindered by immune dysfunction and there is limited high-quality literature available. The aim of this work therefore was to compare immune responses of standard dose (SD) with high-dose accelerated (HDA) vaccination in cirrhotic patients. ",

keywords = "cirrhosis, Hepatitis A, Hepatitis B, Vaccination, Patient outcomes",

author = "Wigg, {Alan J.} and Rachel Wundke and Rosemary McCormick and Muller, {Kate R.} and Jeyamani Ramachandran and Narayana, {Sumudu K.} and Woodman, {Richard J.}",

year = "2019",

month = may,

doi = "10.1016/j.cgh.2018.08.047",

language = "English",

volume = "17",

pages = "1210--1212.e1",

journal = "Clinical Gastroenterology and Hepatology",

issn = "1542-3565",

publisher = "W.B. Saunders Ltd",

number = "6",

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TY - JOUR

T1 - Efficacy of High-Dose, Rapid, Hepatitis A and B Vaccination Schedules in Patients With Cirrhosis

AU - Wigg, Alan J.

AU - Wundke, Rachel

AU - McCormick, Rosemary

AU - Muller, Kate R.

AU - Ramachandran, Jeyamani

AU - Narayana, Sumudu K.

AU - Woodman, Richard J.

PY - 2019/5

Y1 - 2019/5

N2 - Patients with cirrhosis have increased morbidity from hepatitis A virus (HAV) and hepatitis B virus (HBV) infections, and vaccination against these infections is an important standard of care. 1,2 However, vaccination in patients with cirrhosis is hindered by immune dysfunction and there is limited high-quality literature available. The aim of this work therefore was to compare immune responses of standard dose (SD) with high-dose accelerated (HDA) vaccination in cirrhotic patients.

AB - Patients with cirrhosis have increased morbidity from hepatitis A virus (HAV) and hepatitis B virus (HBV) infections, and vaccination against these infections is an important standard of care. 1,2 However, vaccination in patients with cirrhosis is hindered by immune dysfunction and there is limited high-quality literature available. The aim of this work therefore was to compare immune responses of standard dose (SD) with high-dose accelerated (HDA) vaccination in cirrhotic patients.

KW - cirrhosis

KW - Hepatitis A

KW - Hepatitis B

KW - Vaccination

KW - Patient outcomes

UR - http://www.scopus.com/inward/record.url?scp=85063128756&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2018.08.047

DO - 10.1016/j.cgh.2018.08.047

M3 - Short survey

C2 - 30144521

AN - SCOPUS:85063128756

SN - 1542-3565

VL - 17

SP - 1210-1212.e1

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 6

ER -

Efficacy of High-Dose, Rapid, Hepatitis A and B Vaccination Schedules in Patients With Cirrhosis

Abstract

Keywords

UN SDGs

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