Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference

M.D. Robson; D.J. Tyler; J.B. Selvanayagam; J.M. Francis; S. Neubauer

Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference

M.D. Robson, D.J. Tyler, J.B. Selvanayagam, J.M. Francis, S. Neubauer

Research output: Contribution to conference › Abstract › peer-review

Abstract

Sodium concentrations in the human heart increase during ischemia due to failure of the Na-K pump, which results in increases in intracellular Sodium (23Na). This has been demonstrated extensively in animal systems, and has been demonstrated to a lesser extent in humans. Here we describe some technical developments that further advance this field. 23Na exists as a 3/2-spin nucleus its quadrapolar moment results in it having bi-exponential relaxation under typical biological conditions. The relative concentration of these two relaxation components, and T2’s of each of these components may indicate the environment of the nucleus. The sum of these two components yields the total sodium concentration.

Original language	English
Pages	1980-1980
Number of pages	1
Publication status	Published - 2006
Externally published	Yes
Event	ISMRM 14th Scientific Meeting & Exhibition - Seattle, United States Duration: 6 May 2006 → 12 May 2006 Conference number: 14th https://www.ismrm.org/06/index.htm

Conference

Conference	ISMRM 14th Scientific Meeting & Exhibition
Abbreviated title	ISMRM
Country/Territory	United States
City	Seattle
Period	6/05/06 → 12/05/06
Internet address	https://www.ismrm.org/06/index.htm

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https://cds.ismrm.org/protected/06MProceedings/PDFfiles/01980.pdfLicence: In Copyright

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Robson, M. D., Tyler, D. J., Selvanayagam, J. B., Francis, J. M., & Neubauer, S. (2006). Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference. 1980-1980. Abstract from ISMRM 14th Scientific Meeting & Exhibition, Seattle, United States. https://cds.ismrm.org/protected/06MProceedings/PDFfiles/01980.pdf

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title = "Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference",

abstract = "Sodium concentrations in the human heart increase during ischemia due to failure of the Na-K pump, which results in increases in intracellular Sodium (23Na). This has been demonstrated extensively in animal systems, and has been demonstrated to a lesser extent in humans. Here we describe some technical developments that further advance this field. 23Na exists as a 3/2-spin nucleus its quadrapolar moment results in it having bi-exponential relaxation under typical biological conditions. The relative concentration of these two relaxation components, and T2{\textquoteright}s of each of these components may indicate the environment of the nucleus. The sum of these two components yields the total sodium concentration.",

author = "M.D. Robson and D.J. Tyler and J.B. Selvanayagam and J.M. Francis and S. Neubauer",

year = "2006",

language = "English",

pages = "1980--1980",

note = "ISMRM 14th Scientific Meeting & Exhibition, ISMRM ; Conference date: 06-05-2006 Through 12-05-2006",

url = "https://www.ismrm.org/06/index.htm",

}

Robson, MD, Tyler, DJ, Selvanayagam, JB, Francis, JM & Neubauer, S 2006, 'Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference', ISMRM 14th Scientific Meeting & Exhibition, Seattle, United States, 6/05/06 - 12/05/06 pp. 1980-1980. <https://cds.ismrm.org/protected/06MProceedings/PDFfiles/01980.pdf>

TY - CONF

T1 - Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference

AU - Robson, M.D.

AU - Tyler, D.J.

AU - Selvanayagam, J.B.

AU - Francis, J.M.

AU - Neubauer, S.

N1 - Conference code: 14th

PY - 2006

Y1 - 2006

N2 - Sodium concentrations in the human heart increase during ischemia due to failure of the Na-K pump, which results in increases in intracellular Sodium (23Na). This has been demonstrated extensively in animal systems, and has been demonstrated to a lesser extent in humans. Here we describe some technical developments that further advance this field. 23Na exists as a 3/2-spin nucleus its quadrapolar moment results in it having bi-exponential relaxation under typical biological conditions. The relative concentration of these two relaxation components, and T2’s of each of these components may indicate the environment of the nucleus. The sum of these two components yields the total sodium concentration.

AB - Sodium concentrations in the human heart increase during ischemia due to failure of the Na-K pump, which results in increases in intracellular Sodium (23Na). This has been demonstrated extensively in animal systems, and has been demonstrated to a lesser extent in humans. Here we describe some technical developments that further advance this field. 23Na exists as a 3/2-spin nucleus its quadrapolar moment results in it having bi-exponential relaxation under typical biological conditions. The relative concentration of these two relaxation components, and T2’s of each of these components may indicate the environment of the nucleus. The sum of these two components yields the total sodium concentration.

UR - https://cds.ismrm.org/protected/06MProceedings/

M3 - Abstract

SP - 1980

EP - 1980

T2 - ISMRM 14th Scientific Meeting & Exhibition

Y2 - 6 May 2006 through 12 May 2006

ER -

Efficient Quantitative 23Na Concentrations of Fast and Slow T2 Components in the Human Heart Using UTE-CSI and the Blood Pool as a Reference

Abstract

Conference

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