Electroretinogram responses in myopia: a review

Satish Kumar Gupta, Ranjay Chakraborty, Pavan Kumar Verkicharla

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Abstract

The stretching of a myopic eye is associated with several structural and functional changes in the retina and posterior segment of the eye. Recent research highlights the role of retinal signaling in ocular growth. Evidence from studies conducted on animal models and humans suggests that visual mechanisms regulating refractive development are primarily localized at the retina and that the visual signals from the retinal periphery are also critical for visually guided eye growth. Therefore, it is important to study the structural and functional changes in the retina in relation to refractive errors. This review will specifically focus on electroretinogram (ERG) changes in myopia and their implications in understanding the nature of retinal functioning in myopic eyes. Based on the available literature, we will discuss the fundamentals of retinal neurophysiology in the regulation of vision-dependent ocular growth, findings from various studies that investigated global and localized retinal functions in myopia using various types of ERGs.

Original languageEnglish
Number of pages19
JournalDocumenta Ophthalmologica
Early online date17 Nov 2021
DOIs
Publication statusE-pub ahead of print - 17 Nov 2021

Keywords

  • Axial length
  • Electroretinogram (ERG)
  • Myopia
  • Neurons
  • Neurophysiology
  • Retina

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