Estimation of population specific values of theta for sequence-based STR profiles

Yao Yuan Liu; Jo Anne Bright; Duncan Taylor; Maarten Kruijver; John Buckleton

doi:10.1016/j.fsigen.2023.102973

Estimation of population specific values of theta for sequence-based STR profiles

Yao Yuan Liu
, Jo Anne Bright
, Duncan Taylor
, Maarten Kruijver
, John Buckleton

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We describe the estimation of θ (theta) values from autosomal STR sequencing data for five metapopulations. The data were compiled from 20 publications and included 39 datasets comprising a total of 7005 samples. The estimates are suitable for use within the calculation of match probabilities in forensic casework. We also have constructed a phylogenetic tree using this data that aligns with our understanding of human evolution.

Original language	English
Article number	102973
Number of pages	6
Journal	Forensic Science International: Genetics
Volume	68
Early online date	28 Oct 2023
DOIs	https://doi.org/10.1016/j.fsigen.2023.102973
Publication status	Published - Jan 2024

Keywords

Forensic STRs
NGS vs CE
Phylogenetic tree
Population genetics
Sequence variation
θ

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10.1016/j.fsigen.2023.102973Licence: In Copyright

Cite this

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abstract = "We describe the estimation of θ (theta) values from autosomal STR sequencing data for five metapopulations. The data were compiled from 20 publications and included 39 datasets comprising a total of 7005 samples. The estimates are suitable for use within the calculation of match probabilities in forensic casework. We also have constructed a phylogenetic tree using this data that aligns with our understanding of human evolution.",

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AB - We describe the estimation of θ (theta) values from autosomal STR sequencing data for five metapopulations. The data were compiled from 20 publications and included 39 datasets comprising a total of 7005 samples. The estimates are suitable for use within the calculation of match probabilities in forensic casework. We also have constructed a phylogenetic tree using this data that aligns with our understanding of human evolution.

KW - Forensic STRs

KW - NGS vs CE

KW - Phylogenetic tree

KW - Population genetics

KW - Sequence variation

KW - θ

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DO - 10.1016/j.fsigen.2023.102973

M3 - Article

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VL - 68

JO - Forensic Science International: Genetics

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ER -

Estimation of population specific values of theta for sequence-based STR profiles

Abstract

Keywords

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