Evaluation of a monoclonal antibody-based test for detection of Helicobacter pylori-Specific antigen in stool samples from mice

Julia Crone; Erin Symonds; Fiona Campbell; Ross Butler

doi:10.1128/CDLI.11.4.799-800.2004

Evaluation of a monoclonal antibody-based test for detection of Helicobacter pylori-Specific antigen in stool samples from mice

Julia Crone, Erin Symonds, Fiona Campbell, Ross Butler

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6 Citations (Scopus)

Abstract

A test using monoclonal antibodies for detection of antigen in stool samples was compared with culture and histology for noninfected (n = 25), Helicobacter pylori-infected (n = 25), and Helicobacter felis-infected (n = 6) mice. Sensitivity and specificity were 96%. The monoclonal antibody-based test is therefore a noninvasive technique that is able to diagnose H. pylori infection in mice.

Original language	English
Pages (from-to)	799-800
Number of pages	2
Journal	Clinical and Diagnostic Laboratory Immunology
Volume	11
Issue number	4
DOIs	https://doi.org/10.1128/CDLI.11.4.799-800.2004
Publication status	Published - Jul 2004
Externally published	Yes

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AB - A test using monoclonal antibodies for detection of antigen in stool samples was compared with culture and histology for noninfected (n = 25), Helicobacter pylori-infected (n = 25), and Helicobacter felis-infected (n = 6) mice. Sensitivity and specificity were 96%. The monoclonal antibody-based test is therefore a noninvasive technique that is able to diagnose H. pylori infection in mice.

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Evaluation of a monoclonal antibody-based test for detection of Helicobacter pylori-Specific antigen in stool samples from mice

Abstract

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