Evaluation of Vitek2 and Etest for Streptococcus pneumoniae susceptibility to penicillin and ceftriaxone

Caitlyn Sun; Dabah Moukachar; Xiao Chen; Kelly Papanaoum; David L. Gordon

doi:10.1016/j.jinf.2025.106480

Evaluation of Vitek2 and Etest for Streptococcus pneumoniae susceptibility to penicillin and ceftriaxone

Caitlyn Sun
, Dabah Moukachar
, Xiao Chen
, Kelly Papanaoum
, David L. Gordon

College of Medicine and Public Health

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

39 Downloads (Pure)

Abstract

To the Editor,
Accurate Minimum Inhibitory Concentration (MIC) determination for β-lactam antibiotics is essential for the management of invasive Streptococcus pneumoniae infections. Unlike many organisms where a single breakpoint is adequate to determine susceptibility, S. pneumoniae has differing breakpoints for meningitis and non-meningitis syndromes. As such, inaccurate MIC determination can drastically alter the likelihood of therapeutic success...

Original language	English
Article number	106480
Number of pages	3
Journal	Journal of Infection
Volume	90
Issue number	4
DOIs	https://doi.org/10.1016/j.jinf.2025.106480
Publication status	Published - Apr 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Streptococcus pneumoniae
management

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10.1016/j.jinf.2025.106480Licence: CC BY-NC-ND

Final published versionFinal published version, 589 KBLicence: CC BY-NC-ND

Cite this

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title = "Evaluation of Vitek2 and Etest for Streptococcus pneumoniae susceptibility to penicillin and ceftriaxone",

abstract = "To the Editor, Accurate Minimum Inhibitory Concentration (MIC) determination for β-lactam antibiotics is essential for the management of invasive Streptococcus pneumoniae infections. Unlike many organisms where a single breakpoint is adequate to determine susceptibility, S. pneumoniae has differing breakpoints for meningitis and non-meningitis syndromes. As such, inaccurate MIC determination can drastically alter the likelihood of therapeutic success...",

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volume = "90",

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T1 - Evaluation of Vitek2 and Etest for Streptococcus pneumoniae susceptibility to penicillin and ceftriaxone

AU - Sun, Caitlyn

AU - Moukachar, Dabah

AU - Chen, Xiao

AU - Papanaoum, Kelly

AU - Gordon, David L.

PY - 2025/4

Y1 - 2025/4

N2 - To the Editor, Accurate Minimum Inhibitory Concentration (MIC) determination for β-lactam antibiotics is essential for the management of invasive Streptococcus pneumoniae infections. Unlike many organisms where a single breakpoint is adequate to determine susceptibility, S. pneumoniae has differing breakpoints for meningitis and non-meningitis syndromes. As such, inaccurate MIC determination can drastically alter the likelihood of therapeutic success...

AB - To the Editor, Accurate Minimum Inhibitory Concentration (MIC) determination for β-lactam antibiotics is essential for the management of invasive Streptococcus pneumoniae infections. Unlike many organisms where a single breakpoint is adequate to determine susceptibility, S. pneumoniae has differing breakpoints for meningitis and non-meningitis syndromes. As such, inaccurate MIC determination can drastically alter the likelihood of therapeutic success...

KW - Streptococcus pneumoniae

KW - management

UR - https://www.scopus.com/pages/publications/105001236481

U2 - 10.1016/j.jinf.2025.106480

DO - 10.1016/j.jinf.2025.106480

M3 - Letter

AN - SCOPUS:105001236481

SN - 0163-4453

VL - 90

JO - Journal of Infection

JF - Journal of Infection

IS - 4

M1 - 106480

ER -

Evaluation of Vitek2 and Etest for Streptococcus pneumoniae susceptibility to penicillin and ceftriaxone

Abstract

UN SDGs

Keywords

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