Excessive Daytime Sleepiness Increases the Risk of Motor Vehicle Crash in Obstructive Sleep Apnea

Kim L. Ward, David R. Hillman, Alan James, Alexandra P. Bremner, Laila Simpson, Matthew N. Cooper, Lyle J. Palmer, Annette C. Fedson, Sutapa Mukherjee

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

Study Objectives: (1) To describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA); and (2) to investigate MVC risk factors in OSA patients. Methods: A retrospective case-series observational study was conducted using data from the West Australian Sleep Health Study at a tertiary hospital-based sleep clinic. Participants were patients (N = 2,673) referred for assessment of suspected sleep disordered breathing. Questionnaire data were collected including age, sex, years of driving, near-misses and MVCs, sleepiness, and consumption of alcohol and caffeinated drinks. Overnight laboratory-based polysomnography was performed using standard methodology.1 Poisson univariate and negative binomial multivariable regression models were used to investigate associations between risk factors and MVC and nearmiss risk in patients with untreated OSA. Results: In patients with untreated OSA, the crash rate was 0.06 MVC/person-year compared with the general community crash rate of 0.02 MVC/person-year. The rate ratio comparing very sleepy men with normal men was 4.68 (95% CI 3.07, 7.14) for near-misses and 1.27 (95% CI 1.00, 1.61) for crashes, after adjusting for confounders. In women there was a signifi cant association with sleepiness score (p = 0.02) but no dose effect across quartiles. Conclusions: Untreated OSA is associated with an increased risk of near-misses in men and women and an increased risk of MVCs in very sleepy men. There is a strong association between excessive daytime sleepiness and increased report of near-misses. Our data support the observation that it is those patients with increased sleepiness regardless of OSA severity who are most at risk.

Original languageEnglish
Pages (from-to)1013-1021
Number of pages9
JournalJournal of Clinical Sleep Medicine
Volume9
Issue number10
DOIs
Publication statusPublished - 15 Oct 2013
Externally publishedYes

Keywords

  • Gender
  • Motor vehicle crashes
  • Near-misses
  • Obstructive sleep apnea
  • Severity
  • Sleepiness

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