TY - JOUR
T1 - Expert consensus document
T2 - Advances in the diagnosis and classification of gastric and intestinal motility disorders
AU - International Working Group for Disorders of Gastrointestinal Motility and Function
AU - Keller, Jutta
AU - Bassotti, Gabrio
AU - Clarke, John
AU - Dinning, Phil
AU - Fox, Mark
AU - Grover, Madhusudan
AU - Hellström, Per M.
AU - Ke, Meiyun
AU - Layer, Peter
AU - Malagelada, Carolina
AU - Parkman, Henry P.
AU - Scott, S. Mark
AU - Tack, Jan
AU - Simren, Magnus
AU - Törnblom, Hans
AU - Camilleri, Michael
N1 - This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Disturbances of gastric, intestinal and colonic motor and sensory functions affect a large proportion of the population worldwide, impair quality of life and cause considerable health-care costs. Assessment of gastrointestinal motility in these patients can serve to establish diagnosis and to guide therapy. Major advances in diagnostic techniques during the past 5-10 years have led to this update about indications for and selection and performance of currently available tests. As symptoms have poor concordance with gastrointestinal motor dysfunction, clinical motility testing is indicated in patients in whom there is no evidence of causative mucosal or structural diseases such as inflammatory or malignant disease. Transit tests using radiopaque markers, scintigraphy, breath tests and wireless motility capsules are noninvasive. Other tests of gastrointestinal contractility or sensation usually require intubation, typically represent second-line investigations limited to patients with severe symptoms and are performed at only specialized centres. This Consensus Statement details recommended tests as well as useful clinical alternatives for investigation of gastric, small bowel and colonic motility. The article provides recommendations on how to classify gastrointestinal motor disorders on the basis of test results and describes how test results guide treatment decisions.
AB - Disturbances of gastric, intestinal and colonic motor and sensory functions affect a large proportion of the population worldwide, impair quality of life and cause considerable health-care costs. Assessment of gastrointestinal motility in these patients can serve to establish diagnosis and to guide therapy. Major advances in diagnostic techniques during the past 5-10 years have led to this update about indications for and selection and performance of currently available tests. As symptoms have poor concordance with gastrointestinal motor dysfunction, clinical motility testing is indicated in patients in whom there is no evidence of causative mucosal or structural diseases such as inflammatory or malignant disease. Transit tests using radiopaque markers, scintigraphy, breath tests and wireless motility capsules are noninvasive. Other tests of gastrointestinal contractility or sensation usually require intubation, typically represent second-line investigations limited to patients with severe symptoms and are performed at only specialized centres. This Consensus Statement details recommended tests as well as useful clinical alternatives for investigation of gastric, small bowel and colonic motility. The article provides recommendations on how to classify gastrointestinal motor disorders on the basis of test results and describes how test results guide treatment decisions.
UR - http://www.scopus.com/inward/record.url?scp=85045939989&partnerID=8YFLogxK
U2 - 10.1038/nrgastro.2018.7
DO - 10.1038/nrgastro.2018.7
M3 - Review article
C2 - 29622808
AN - SCOPUS:85045939989
VL - 15
SP - 291
EP - 308
JO - Nature Reviews: Gastroenterology & Hepatology
JF - Nature Reviews: Gastroenterology & Hepatology
SN - 1759-5053
ER -