TY - JOUR
T1 - Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa
T2 - a comprehensive systematic review and meta-analysis
AU - Tinsae, Techilo
AU - Getinet, Wondale
AU - Fentahun, Setegn
AU - Shumet, Shegaye
AU - Medifu, Girmaw
AU - Andualem, Fantahun
AU - Nakie, Girum
AU - Segon, Tesfaye
AU - Koye, Selam
AU - Tadesse, Gebresilassie
AU - Rtbey, Gidey
PY - 2025/4/25
Y1 - 2025/4/25
N2 - Background: Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals. This study aimed to investigate the prevalence, incidence, and risk factors of post-stroke depression among stroke survivors in Africa. Methods: PubMed, WHO Global Index Medicus, Web of Science, Cochrane Library, Google Scholar, ScienceDirect, HINARI, and Google were the sources of data searching. Literature reporting the prevalence, incidence and risk factors of post-stroke depression in Africa was included. The quality of each study was evaluated using the Newcastle-Ottawa Quality Assessment Scale (NOS). Data were extracted using a Microsoft Excel spreadsheet, and data analysis was performed using STATA version 11. Heterogeneity between studies was checked using the I2 statistical test. Publication bias was checked using Egger’s statistical test and funnel plot. Results: A total of twenty-two relevant studies with 3175 stroke patients were included in this systematic review and meta-analysis. The overall estimated pooled prevalence and incidence of depression among stroke survivors in Africa were found to be 42.5% (95% CI = 26.9, 58.1) and 33.2% (95% CI = 23.3, 43.0), respectively. The subgroup analysis further revealed that Nigeria had the highest prevalence of depression at 47.6% (95% CI: 15.1, 80.1), followed by Ethiopia at 44.4% (95% CI: 28.2, 60.6). This study did not identify any factors that were positively associated with post-stroke depression. Conclusion: The prevalence and incidence of depression among stroke survivors are notably high. Despite the high occurence, this study did not identify specific risk factors positively associated with post-stroke depression. Consequently, addressing post-stroke depression through integrated care models, routine screening, and targeted interventions is crucial for enhancing the quality of life and rehabilitation outcomes for stroke survivors in Africa.
AB - Background: Post-stroke depression is a significant health concern, especially in developing countries. The high prevalence, incidence, and complexity of depression among stroke survivors pose a substantial occurence on vulnerable individuals. This study aimed to investigate the prevalence, incidence, and risk factors of post-stroke depression among stroke survivors in Africa. Methods: PubMed, WHO Global Index Medicus, Web of Science, Cochrane Library, Google Scholar, ScienceDirect, HINARI, and Google were the sources of data searching. Literature reporting the prevalence, incidence and risk factors of post-stroke depression in Africa was included. The quality of each study was evaluated using the Newcastle-Ottawa Quality Assessment Scale (NOS). Data were extracted using a Microsoft Excel spreadsheet, and data analysis was performed using STATA version 11. Heterogeneity between studies was checked using the I2 statistical test. Publication bias was checked using Egger’s statistical test and funnel plot. Results: A total of twenty-two relevant studies with 3175 stroke patients were included in this systematic review and meta-analysis. The overall estimated pooled prevalence and incidence of depression among stroke survivors in Africa were found to be 42.5% (95% CI = 26.9, 58.1) and 33.2% (95% CI = 23.3, 43.0), respectively. The subgroup analysis further revealed that Nigeria had the highest prevalence of depression at 47.6% (95% CI: 15.1, 80.1), followed by Ethiopia at 44.4% (95% CI: 28.2, 60.6). This study did not identify any factors that were positively associated with post-stroke depression. Conclusion: The prevalence and incidence of depression among stroke survivors are notably high. Despite the high occurence, this study did not identify specific risk factors positively associated with post-stroke depression. Consequently, addressing post-stroke depression through integrated care models, routine screening, and targeted interventions is crucial for enhancing the quality of life and rehabilitation outcomes for stroke survivors in Africa.
KW - Depression
KW - Incidence and stroke depression
KW - Post-stroke
KW - Post-stroke depression
KW - Prevalence
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=105003755447&partnerID=8YFLogxK
U2 - 10.1186/s12889-025-22685-5
DO - 10.1186/s12889-025-22685-5
M3 - Article
C2 - 40281530
AN - SCOPUS:105003755447
SN - 1471-2458
VL - 25
JO - BMC Public Health
JF - BMC Public Health
IS - 1
M1 - 1547
ER -
