Extracellular vesicles in cancer nanomedicine.

Vadim Tarasov, Andrey Svistunov, Vladimir Chubarev, Dostdar SA, Brzecka A, Olga Sukocheva, Margarita Neganova, Sergey Klochkov, Siva Somasundaram, Eric Kirkland, Gjumrakch Aliev

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.
Original languageEnglish
Number of pages14
JournalSEMINARS IN CANCER BIOLOGY
DOIs
Publication statusAccepted/In press - 14 Aug 2019

Keywords

  • cancer
  • exosomes
  • nanodrug delivery
  • vaccines
  • extracellular vesicles

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