Extracellular vesicles in cancer nanomedicine.

Vadim V. Tarasov; Andrey A. Svistunov; Vladimir N. Chubarev; Samira A. Dostdar; Alexander V. Sokolov; Anna Brzecka; Olga Sukocheva; Margarita E. Neganova; Sergey G. Klochkov; Siva G. Somasundaram; Cecil E. Kirkland; Gjumrakch Aliev

doi:10.1016/j.semcancer.2019.08.017

Extracellular vesicles in cancer nanomedicine.

Vadim V. Tarasov, Andrey A. Svistunov, Vladimir N. Chubarev, Samira A. Dostdar, Alexander V. Sokolov, Anna Brzecka, Olga Sukocheva, Margarita E. Neganova, Sergey G. Klochkov, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch Aliev

College of Nursing and Health Sciences

Research output: Contribution to journal › Review article › peer-review

87 Citations (Scopus)

Abstract

To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.

Original language	English
Pages (from-to)	212-225
Number of pages	14
Journal	SEMINARS IN CANCER BIOLOGY
Volume	69
DOIs	https://doi.org/10.1016/j.semcancer.2019.08.017
Publication status	Published - Feb 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Extracellular vesicles
Nanodrug delivery
Vaccines
Exosomes
Cancer

Access to Document

10.1016/j.semcancer.2019.08.017Licence: In Copyright

Cite this

@article{74794e1761e04818967961e71ffd2369,

title = "Extracellular vesicles in cancer nanomedicine.",

abstract = "To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.",

keywords = "Extracellular vesicles, Nanodrug delivery, Vaccines, Exosomes, Cancer",

author = "Tarasov, {Vadim V.} and Svistunov, {Andrey A.} and Chubarev, {Vladimir N.} and Dostdar, {Samira A.} and Sokolov, {Alexander V.} and Anna Brzecka and Olga Sukocheva and Neganova, {Margarita E.} and Klochkov, {Sergey G.} and Somasundaram, {Siva G.} and Kirkland, {Cecil E.} and Gjumrakch Aliev",

year = "2021",

month = feb,

doi = "10.1016/j.semcancer.2019.08.017",

language = "English",

volume = "69",

pages = "212--225",

journal = "SEMINARS IN CANCER BIOLOGY",

issn = "1044-579X",

publisher = "Academic Press",

}

TY - JOUR

T1 - Extracellular vesicles in cancer nanomedicine.

AU - Tarasov, Vadim V.

AU - Svistunov, Andrey A.

AU - Chubarev, Vladimir N.

AU - Dostdar, Samira A.

AU - Sokolov, Alexander V.

AU - Brzecka, Anna

AU - Sukocheva, Olga

AU - Neganova, Margarita E.

AU - Klochkov, Sergey G.

AU - Somasundaram, Siva G.

AU - Kirkland, Cecil E.

AU - Aliev, Gjumrakch

PY - 2021/2

Y1 - 2021/2

N2 - To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.

AB - To date, a lot of nanotechnological optitions are available for targeted drug delivery. Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport, communication, and signaling. Recent research has focused on EVs as natural nanoparticles for drug delivery. This review sheds light on the application of EVs in cancer therapy, such as targeted chemotherapy, gene therapy, and vaccine development. Aspects of biogenesis, isolation, targeting, and loading of EVs are discussed in detail.

KW - Extracellular vesicles

KW - Nanodrug delivery

KW - Vaccines

KW - Exosomes

KW - Cancer

UR - http://www.scopus.com/inward/record.url?scp=85070919844&partnerID=8YFLogxK

U2 - 10.1016/j.semcancer.2019.08.017

DO - 10.1016/j.semcancer.2019.08.017

M3 - Review article

SN - 1044-579X

VL - 69

SP - 212

EP - 225

JO - SEMINARS IN CANCER BIOLOGY

JF - SEMINARS IN CANCER BIOLOGY

ER -

Extracellular vesicles in cancer nanomedicine.

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this