Abstract
Purpose of the Review
Preeclampsia and the Hypertensive Disorders of Pregnancy (HDP) occur more frequently amongst Indigenous women and can have short- and long-term impacts on maternal and infant health and wellbeing. To understand factors associated with increased risk for Indigenous women a systematic review and meta-analysis was conducted. The PRISMA guidelines were adhered to, and the review protocol was registered on PROSPERO (Registration CRD42023381847). EndNote, Covidence and Excel were used to screen and extract data, with studies assessed using JBI critical appraisal tools.
Recent Findings
Seven studies from Canada, Australia, and the United States (none from New Zealand) were included in this review. Meta-analysis showed women classified as overweight (OR 1.32, 95% CI: 1.09–1.60), obese (OR 1.88, 95% CI: 1.57–2.25), or having high mean BMI (MD 3.02 95% CI: 1.72–4.31), high mean systolic blood pressure (MD 15.19 95% CI: 12.83–17.541), or high mean diastolic blood pressure (MD 15.26 95% CI: 13.05–17.47), pre-pregnancy diabetes (OR 3.63, 95% CI: 1.66–17.94), or high microalbuminuria (OR 2.76, 95% CI: 1.40–5.43) were more likely to be diagnosed with preeclampsia. Smoking (OR 0.77, 95% CI: 0.58–1.03), alcohol consumption (OR 1.70, 95% CI: 0.76–3.81), and gestational diabetes (OR 1.74, 95% CI: 0.90–3.37) were not associated with preeclampsia.
Summary
Understanding factors associated with increased preeclampsia/HDP risk amongst Indigenous women is important to minimising adverse perinatal events and future health complications. This review demonstrates current gaps in the evidence, specifically in relation to social, economic, and environmental factors.
Preeclampsia and the Hypertensive Disorders of Pregnancy (HDP) occur more frequently amongst Indigenous women and can have short- and long-term impacts on maternal and infant health and wellbeing. To understand factors associated with increased risk for Indigenous women a systematic review and meta-analysis was conducted. The PRISMA guidelines were adhered to, and the review protocol was registered on PROSPERO (Registration CRD42023381847). EndNote, Covidence and Excel were used to screen and extract data, with studies assessed using JBI critical appraisal tools.
Recent Findings
Seven studies from Canada, Australia, and the United States (none from New Zealand) were included in this review. Meta-analysis showed women classified as overweight (OR 1.32, 95% CI: 1.09–1.60), obese (OR 1.88, 95% CI: 1.57–2.25), or having high mean BMI (MD 3.02 95% CI: 1.72–4.31), high mean systolic blood pressure (MD 15.19 95% CI: 12.83–17.541), or high mean diastolic blood pressure (MD 15.26 95% CI: 13.05–17.47), pre-pregnancy diabetes (OR 3.63, 95% CI: 1.66–17.94), or high microalbuminuria (OR 2.76, 95% CI: 1.40–5.43) were more likely to be diagnosed with preeclampsia. Smoking (OR 0.77, 95% CI: 0.58–1.03), alcohol consumption (OR 1.70, 95% CI: 0.76–3.81), and gestational diabetes (OR 1.74, 95% CI: 0.90–3.37) were not associated with preeclampsia.
Summary
Understanding factors associated with increased preeclampsia/HDP risk amongst Indigenous women is important to minimising adverse perinatal events and future health complications. This review demonstrates current gaps in the evidence, specifically in relation to social, economic, and environmental factors.
| Original language | English |
|---|---|
| Article number | 10 |
| Number of pages | 16 |
| Journal | CURRENT HYPERTENSION REPORTS |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 20 Feb 2025 |
Keywords
- Hypertension
- Indigenous
- Pre-eclampsia [MESH]
- Pregnancy
- Pregnant women [MESH]
- Risk factors [MESH]
