Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

Georgios Tsiminis; Thomas Klaric; Erik Schartner; Stephen Warren-Smith; Martin Lewis; Simon Koblar; Tanya Monro

doi:10.1117/12.2071261

Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

Georgios Tsiminis, Thomas Klaric, Erik Schartner, Stephen Warren-Smith, Martin Lewis, Simon Koblar, Tanya Monro

Research output: Contribution to conference › Paper › peer-review

1 Citation (Scopus)

Abstract

We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.

Original language	English
DOIs	https://doi.org/10.1117/12.2071261
Publication status	Published - 1 Jan 2014
Event	23rd International Conference on Optical Fibre Sensors - Duration: 2 Jun 2014 → …

Conference

Conference	23rd International Conference on Optical Fibre Sensors
Period	2/06/14 → …

Keywords

Fluorescence detection
In-vivo sensor
Optical fibre sensor
Photochemical stroke

Access to Document

10.1117/12.2071261

Cite this

@conference{0a19c381b0e9435bb25144aab3d3e150,

title = "Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain",

abstract = "We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.",

keywords = "Fluorescence detection, In-vivo sensor, Optical fibre sensor, Photochemical stroke",

author = "Georgios Tsiminis and Thomas Klaric and Erik Schartner and Stephen Warren-Smith and Martin Lewis and Simon Koblar and Tanya Monro",

year = "2014",

month = jan,

day = "1",

doi = "10.1117/12.2071261",

language = "English",

note = "23rd International Conference on Optical Fibre Sensors ; Conference date: 02-06-2014",

}

TY - CONF

T1 - Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

AU - Tsiminis, Georgios

AU - Klaric, Thomas

AU - Schartner, Erik

AU - Warren-Smith, Stephen

AU - Lewis, Martin

AU - Koblar, Simon

AU - Monro, Tanya

PY - 2014/1/1

Y1 - 2014/1/1

N2 - We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.

AB - We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.

KW - Fluorescence detection

KW - In-vivo sensor

KW - Optical fibre sensor

KW - Photochemical stroke

UR - http://www.scopus.com/inward/record.url?scp=84903200761&partnerID=8YFLogxK

U2 - 10.1117/12.2071261

DO - 10.1117/12.2071261

M3 - Paper

T2 - 23rd International Conference on Optical Fibre Sensors

Y2 - 2 June 2014

ER -

Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

Abstract

Conference

Keywords

Access to Document

Other files and links

Fingerprint

Cite this