Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

Georgios Tsiminis, Thomas Klaric, Erik Schartner, Stephen Warren-Smith, Martin Lewis, Simon Koblar, Tanya Monro

    Research output: Contribution to conferencePaper

    Abstract

    We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.

    Original languageEnglish
    DOIs
    Publication statusPublished - 1 Jan 2014
    Event23rd International Conference on Optical Fibre Sensors -
    Duration: 2 Jun 2014 → …

    Conference

    Conference23rd International Conference on Optical Fibre Sensors
    Period2/06/14 → …

    Keywords

    • Fluorescence detection
    • In-vivo sensor
    • Optical fibre sensor
    • Photochemical stroke

    Fingerprint Dive into the research topics of 'Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain'. Together they form a unique fingerprint.

  • Cite this

    Tsiminis, G., Klaric, T., Schartner, E., Warren-Smith, S., Lewis, M., Koblar, S., & Monro, T. (2014). Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain. Paper presented at 23rd International Conference on Optical Fibre Sensors, . https://doi.org/10.1117/12.2071261